Electron-deficient porphyrins and processes and intermediates fo

Details Electron-deficient porphyrins and processes and intermediates fo Electron-deficient porphyrins and processes and intermediates fo

1994-04-28

1997-02-04

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548400, C07D48722

Patent

active

055999247

ABSTRACT:
Electron-deficient porphyrins are provided, as well as processes and intermediates for their preparation. In preferred embodiments, the electron-deficient porphyrins are prepared by condensing pyrrole derivatives and removing water thus formed from the resulting reaction mixture.

REFERENCES:
patent: 3579533 (1971-05-01), Yalman
patent: 3687863 (1972-08-01), Wacher
patent: 3897255 (1975-07-01), Erickson
patent: 3899334 (1975-08-01), Erickson
patent: 4360703 (1982-11-01), Bolton et al.
patent: 4647478 (1987-03-01), Formanek et al.
patent: 4657902 (1987-04-01), Kappas et al.
patent: 4668670 (1987-05-01), Rideout et al.
patent: 4792836 (1988-12-01), Quinlan
patent: 4892941 (1990-01-01), Dolphin et al.
patent: 4895682 (1990-01-01), Ellis, Jr. et al.
patent: 4957615 (1990-09-01), Ushizawa et al.
patent: 4970348 (1990-11-01), Ellis, Jr. et al.
patent: 4986256 (1991-01-01), Cohen et al.
patent: 4988808 (1991-01-01), Morgan et al.
patent: 5051337 (1991-09-01), Sakoda et al.
patent: 5091502 (1992-02-01), Narang et al.
patent: 5103027 (1992-04-01), Shum et al.
patent: 5118886 (1992-06-01), Ellis, Jr. et al.
patent: 5120453 (1992-06-01), Frame et al.
patent: 5120882 (1992-06-01), Ellis, Jr. et al.
patent: 5120886 (1992-06-01), Lyons et al.
patent: 5164944 (1992-11-01), Benton et al.
patent: 5169944 (1992-12-01), Nelson et al.
patent: 5171741 (1992-12-01), Dougherty
patent: 5200481 (1993-04-01), Sounik et al.
patent: 5212300 (1993-05-01), Ellis, Jr. et al.
patent: 5241062 (1993-08-01), Wijesekera et al.
patent: 5252730 (1993-10-01), Mackey
patent: 5280115 (1994-01-01), Ellis, Jr. et al.
patent: 5371199 (1994-12-01), Therien et al.
patent: 5405957 (1995-04-01), Tang et al.
Sanders et al. J. Org. Chem., 53, pp. 5272-5281, 1988.
Aoyagi et al. Chem. Letters 1988, pp. 1891-1894.
Anderson, H. L. "Meso-Alkynyl prophyrins" Tet. Letts. 33: 1101-1104 (1992).
Arnold et al, "Some Reactions of Meso-Formyloctaethylporphyrin" JCS Perkin I: 366-370 (1978).
Arnold and Nitschinsk, "The Preparation of Novel Porphyrins and Bis(Porphyrins) Using Palladium Catalysed Coupling Reactions" Tet. Letts. 34: 693-696 (1993).
Azizian et al., "Synthesis of Organotrialkystannanes. The Reaction Between Organic Halides and Hexaalskydistannanes in The Presence of Paladium Complexes" Organomet. Chem. 215: 49-58 (1981).
Barbero et al., "The Stannyl-Cupration of Acetylenes and the Reaction of the Intermediate Cuprates with Electrophiles as a synthesis of Substituted Vinylstannanes" J. Chem. Soc. Chem. Commun. 351-353 (1992).
Bonnett, R. Chapter 1 entitled "Nomenclature" The Porphyrins, Dolphin, ed., vol. I, Academic Press, New York 1-27 (1978).
Cadiot and Chodkiewicz in Viche (ed), Chapter 9 entitled "Coupling of Acetylene" from Acetylenes 597-647, Marcel Dehker, NY (1964).
Callot, "Bromination of m-tetraphenylporphine. Preparation of alkyl derivatives and polycyanoporphines" Chem. Abstracts vol. 81: #105479p (p.530) (1974).
Clezy, P. S. et al., Chapter 6 "Synthesis of Porphyrins from Oxobilane Intermediates" The Porphyrins, Dolphin, ed. vol. I, Academic Press, New York, 265-288 (1978).
Cohen, Jack S., "Use of Paramagnetic Metalloporphyrins as Contrast Agents for Tumors in NMR Imaging" (Feb. 1985) U.S. Dept. of Commerce, Springfield, VA 22161 **.
Collman et al., Principles & Applications of Organotransition Metal Chemistry, Chapter 14 710-738 University Science Books, 1987, Mill Valley, CA.
Drummond et al., "Tin(Sn.sup.++++)-Diiododeuteroporphyrin; an in Vitro and in vivo Inhibitor of Heme Oxygenase with Substantially Reduced Photoactive Properties", J. of Pharmacology and Experimental Therapeutics 257: 1109-1113 (1991).
DiNello, Robert K. et al., Chapter 7 entitled "Isolation and Modification of Natural Porphyrins," The Porphyrins, Dolphin, ed. vol. I, Academic Press, New York, 289-339 (1978).
Durand et al., "Mechanistic Aspects of the Catalytic Reduction of Dioxygen by Cofacial Metalloporphyrins" J. Am. Chem. Soc. 105: 2710-2718 (1983).
Ebert & Rieke, "Direct Formation of Organocopper Compounds by Oxidative Addition of Zerovalent Copper to Organic Halides" J. Org. Chem. 49: 5280-5282 (1984).
Ebert & Rieke, "Preparation of Aryl, Alkynyl, and Vinyl Organocopper Compounds by the Oxidative Addition of Zerovalent Copper to Carbon-Halogen Bonds" J. Org. Chem. 53: 4482-4488 (1988).
Eglinton and McCrae, "The Coupling of Acetylenic Compounds" from Advances in Organic Chemistry vol. 4: 225-328 Raphael et al. Eds, Interscience Publishers, New York-London (1963).
Giround-Godquin, Anne Marie et al., "Metallomesogens: Metal Complexes in Organized Fluid Phases" Angew. Chem. Int. Ed. Engl. 30: 75-402 (1991).
Gonsalves, Rocha, d'A. A. M. et al., "A New Look into the Rothemund meso-Tetraalkyl and Tetraarylporphyrin Synthesis" J. Heterocyclic Chem. 22: 931-933 (1985).
Greenwood and Earnshaw, Chemistry of the Elements, Pergamon Press, Oxford, 1399-1403 (1984).
Groves et al., "Catalytic Asymmetric Expoxidations with Chiral Iron Porphyrins" J. Am. Chem. Soc. 105: 5791-5796 (1983).
Gunter and Robinson, "Purpurins Bearing Functionality at the 6,16-meso-Positions: Synthesis from 5,15-Disubstituted meso-[.beta.- (Methoxycarbonyl)vinyl]porphyrins" Aust. J. Chem. 43: 1839-1860 (1990).
Hevesi et al., "Synthesis of meso-Tetravinyl Porphyrins Through 1-Selenoallyl Cationic Species" J. Chem. Soc. Chem. Commun. 1725-1727 (1986).
Hayashi, T. et al., "Dichloro[1,1'] -Bis (Diphenylphosphino) Ferrocene]Palladium(II): An Effective Catalyst for Cross-Coupling Reaction of a Secondary Alkyl Grignard Reagent with Organic Halides" Tet. Letts. 21: 1871-1874 (1979).
Helms, Anna et al., "Electron Transfer in Bis-Porphyrin Donor-Acceptor Compounds with Polyphenylene Spacers Shows a Weak Distance Dependence" J. Am. Chem. Soc. 114: 6227-6238 (1992).
Johnson, A. W. Chapter 5 "Synthesis of Porphyrins from 1,19-Dideoxybiladienes-ac and 1,19-Dideoxybilenes-b," The Porphyrins, Dolphin, ed. vol. I, Academic Press, New York, 235-264 (1978).
Kim et al., Chapter 3 entitled "Synthesis of Porphyrins from Monopyrroles" The Porphyrins, Dolphin, ed. vol. I, Academic Press, New York, 85-99 (1978).
Komarov et al., "Synthesis and Some Transformations of .alpha.-Siliconacetylenic Aldehydes" UDS 920-922 (1966).
Kumada, "Nickel and Palladium Complex Catalyzed Cross-Coupling Reactions of Organometallic Reagents with Organic Halides" M. Pure & Appl. Chem. 52: 669-679 (1980).
Lehn, Jean-Marie, "Supramolecular Chemistry-Scope and Perspectives Molecules, Supermolecules, and Molecular Devices" (Nobel Lecture) Angewandte Chemie Int. Ed. in Eng. 27(1): 89-112 (1988).
Lindsey and Wagner, "Investigation of the Synthesis of Ortho-Substituted Tetraphenylporphyrins", J. Org. Chem. 54: 827-836 (1989).
Lindsey et al., "Rothemund and Adler-Longo Reactions Revisited: Synthesis of Tetraphenylporphyrins Under Equilibrium Conditions", J. Org. Chem. 52: 827-836 (1987).
Manka, John S. and Lawrence, David S., "Self-Assembly of a Hydrophobic Groove" Tet. Letts. 30: 7341-7344 (1989).
Mansuy et al., "Asymmetric Epoxidation of Alkenes Catalyzed by a Basket-Handle Iron-Porphyrin Bearing Amino Acids" J. Chem. Soc. Chem. Commun. 155-156 (1985).
Maruyama and Kawabata, "Synthesis and Characterization of Polyyne Porphyrins" Bull Chem. Soc. Jpn.63: 170-175 (1990).
Mauzerall D., Chapter 3 entitled "The Porphyrinogens" The Porphyrins, Dolphin, ed. vol. III, Academic Press, New York, 91-101 (1978).
Minnetian, Ohannes M., et al., "New Synthesis and Reactionso f Some Halogenated Porphyrins" J. Org. Chem. 54: 5567-5574 (1989).
Morris, Ian K. et al., "Syntheses of Novel Substituted Porphyrins by the Mercuration and Palladium/Olefin Methodology" J. Org. Chem. 55: 1231-1236 (1990).
Nagata, Toshi et al., "Synthesis and Optical Properties of Conformationally Constrained Trimeric and Pentameric Porphyrin Arrays" J. Am. Chem. Soc. 112: 3054-3059 (1990).
Nudy, Louis R. et al., "A Study of Bromophrophins" Tetrahedron 40: 2359-2363 (1984).
Osuka et al., "A 1,2-Phenylene-Bridged Porphyrin Dimer--Synthesis, Properties, and Molecular Structure" Angew. Chem. Int. Ed. Engl. 30: 582-584 (1991).
Paine, Chapter 4, entitled "Synthesis of Pyrroles and

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