Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Using direct contact with electrical or electromagnetic...
Patent
1996-10-21
1999-11-23
McKane, Elizabeth
Chemical apparatus and process disinfecting, deodorizing, preser
Process disinfecting, preserving, deodorizing, or sterilizing
Using direct contact with electrical or electromagnetic...
422 23, 422 36, 435 11, 623 2, A61L 208, A01N 100
Patent
active
059894989
ABSTRACT:
A method for sterilizing collagen containing tissue includes crosslinking the tissue to form a crosslinked biological tissue. The tissue is maintained in a hydrated state. The crosslinked, collagen-containing tissue is sterilized by irradiating the tissue with a beam of accelerated electrons. The biological tissue exposed to accelerated electrons is suitable for surgical implantation. The irradiated biological tissue is not significantly degraded following irradiation. The irradiation can be performed on tissue that has been packed in a container in a hydrated state.
REFERENCES:
patent: 3779706 (1973-12-01), Nablo
patent: 4378224 (1983-03-01), Nimni et al.
patent: 4553974 (1985-11-01), Dewanjee
patent: 4647283 (1987-03-01), Carpentier et al.
patent: 4798611 (1989-01-01), Freeman, Jr.
patent: 5096553 (1992-03-01), Ross et al.
patent: 5336616 (1994-08-01), Livesey et al.
patent: 5366746 (1994-11-01), Mendenhall
Beach, P. Maynard, Jr. et al. "Aortic Valve Replacement with Frozen Irradiated Homografts: Long-Term Evaluation," Supplement I to Circulation, vols. XLV and XLVI, May 1972.
Campalani, G. et al. "Aortic valve replacement with frozen irradiated homografts: An 18-year experience," Eur J Cardio-thorac Surgery (1989) 3: 558-561, 1989.
Gonzalez-Lavin, L. et al. "Homograft aortic valve replacement: A five-year experience at the National Heart Hospital, London." J of Thoracic and Cardiovascular Surfery, v.60 No.1, pp. 1-12, Jul. 1970.
Hopkins, Richard A. Cardiac Reconstructions with Allograft Valves. pp. 1,4,9,10, no date avail.
Ionescu, M.I., ed. Biological Tissue in Heart Valve Replacement, pp. 313-331, no date avail.
Inoue, A. "An Experimental Study on Processed Peripheral Nerve Grafting," J. Kyoto Prefect Univ. Med . . . vol. 90 (4), pp. 323-337, 1981.
Malm et al. "An evaluation of aortic valve . . . beam energy," J. of Thoracic and Cardiovascular Surgery, vol.54, No. 4, pp. 471-477, Oct. 1967.
Webster's Ninth New Collegiate Dictionary, Merriam-Webster Inc, 1983, definition of "tissue" p. 1237.
Rangwalla et al., "Electron-Beam Sterilization and its Application to aseptic packaging," Pharm. Technology, Nov. 1985, pp. 36-47.
Dardi Peter S.
McKane Elizabeth
St. Jude Medical Inc.
LandOfFree
Electron-beam sterilization of biological materials does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Electron-beam sterilization of biological materials, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electron-beam sterilization of biological materials will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1217737