Electromagnetic wave absorbing, surface modified magnetic partic

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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424490, 424498, 424600, 424617, 424630, 424635, 424639, 424641, 424644, 424646, 424650, 42840224, A61K 9127

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active

054417465

ABSTRACT:
This invention describes an electromagnetic wave-absorbing surface modified magnetic particle for use in medical applications. The magnetic particles are coated with an amphipathic organic compound and an amphipathic vesicle forming lipid. These particles may be used in a method of treatment of cancer, as well as for the treatment of infectious disease. For cancer treatment the invention comprises providing a patient said coated particles, absorbing the coated particle intracellularly into the cancer cell, and subjecting the patient to an alternating electromagnetic field to inductively heat the magnetic core particle along with the cancer cells. The inductive heating of the magnetic core particle is then continued so as to achieve an increase in intracellular temperature which selectively kills the cancer cells.

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