Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-02-09
1998-07-28
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 5, 435 911, 435 912, 435 71, 536 266, 4221781, 436518, 436149, 5303881, 530300, C12Q 168, C12Q 170, C12P 1934, G01N 3353
Patent
active
057861412
ABSTRACT:
Biomolecule analysis using anodic oxidation of aqueous sodium 9, 10-diphenylanthracene-2-sulfonate (DPAS) and 1- and 2-thianthrenecarboxylic acid (1-THCOOH and 2-THCOOH) in the presence of tri-n-propylamine (TPrA) as a coreactant in aqueous solution produces electrogenerated chemiluminescence (ECL). In addition, the cathodic reduction of DPAS in the presence of peroxydisulfate (S.sub.2 O.sub.8.sup.2-) as a coreactant also produces ECL in an acetonitrile (MeCN)-water solution (1:1 by volume). The oxidation of chlorpromazine (CPZ) produces an ECL emission in the absence of an added coreactant following an unprecedented "self-annihilation" mechanism.
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Bard Allen J.
Leland Jonathan K.
Richards Thomas
Jones W. Gary
Rees Dianne
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