Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Fusion of cells
Reexamination Certificate
2011-03-29
2011-03-29
Ketter, James S (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Fusion of cells
C435S286500, C435S285200, C435S461000, C435S173600
Reexamination Certificate
active
07915044
ABSTRACT:
The present invention relates to an electrofusion microelectrode made of a tube having a first proximal end and a second distal end. The tube has an electrically conductive coating on its exterior surface that extends continually from the first proximal end of the tube toward the second distal end of the tube. Also disclosed is an electrofusion microelectrode unit having an electrofusion microelectrode and a holding tool capable of receiving the electrofusion microelectrode at the second distal end of the tube. The present invention also relates to a system having two or more electrofusion microelectrodes of the present invention and to methods of manipulating cells and/or cellular components using the electrofusion microelectrodes, units, and systems of the present invention.
REFERENCES:
patent: 4371273 (1983-02-01), Kendall et al.
patent: 4441972 (1984-04-01), Pohl
patent: 4923814 (1990-05-01), Marshall, III
patent: 5007995 (1991-04-01), Takahashi et al.
patent: 5128257 (1992-07-01), Baer
patent: 5185922 (1993-02-01), Pendley et al.
patent: 5304120 (1994-04-01), Crandell et al.
patent: 5304486 (1994-04-01), Chang
patent: 5505728 (1996-04-01), Ellman et al.
patent: 5589047 (1996-12-01), Coster et al.
patent: 5650305 (1997-07-01), Hui et al.
patent: 5749837 (1998-05-01), Palermo et al.
patent: 5827736 (1998-10-01), Heller et al.
patent: 5859327 (1999-01-01), Dev et al.
patent: 5983131 (1999-11-01), Weaver et al.
patent: 5993434 (1999-11-01), Dev et al.
patent: 6001617 (1999-12-01), Raptis
patent: 6009345 (1999-12-01), Hofmann
patent: 6077261 (2000-06-01), Behl et al.
patent: 6150148 (2000-11-01), Nanda et al.
patent: 6261815 (2001-07-01), Meyer
patent: 6347247 (2002-02-01), Dev et al.
patent: 6355485 (2002-03-01), Jaroszeski et al.
patent: 6452564 (2002-09-01), Schoen et al.
patent: 7101703 (2006-09-01), Palermo
patent: 7186547 (2007-03-01), Palermo
patent: 2002/0010414 (2002-01-01), Coston et al.
patent: 2002/0019035 (2002-02-01), Tai et al.
patent: 2007/0148758 (2007-06-01), Palermo
Stromburg et al., “Manipulating the Genetic Identity and Biochemical Surface Proteins of Individual Cells with Electric-Field-Induced Fusion,” PNAS 97(1):7-11 (2000).
Stromburg et al., “Microfluidic Device for Combinatorial Fusion of Liposomes and Cells,” Anal. Chem. 73:126-130 (2001).
Rae et al., “Instrument and Techniques Single-Cell Electrroporation,” Pflugers Archiv-European Journal of Physiology (2001).
Haas et al., “Single-Cell Electroporation for Gene Transfer In Vivo,” Neuron 29:583-591 (2001).
Webster's Ninth New Collegiate Dictionary, pp. 470-471, 1983.
Takeuchi et al., “A Reliable Technqiue of Nuclear Transplantation for Immature Mammalian Oocytes,” Human Reproduction 14:1312-1317 (1999).
International Search Report for International Patent Application No. PCT/US06/44394 (Feb. 19, 2008).
Cornell Research Foundation Inc.
Ketter James S
LeClairRyan
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