Electrochemiluminescence detection method for nucleic acid...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C436S094000

Reexamination Certificate

active

07090977

ABSTRACT:
Disclosed is a method for detecting nucleic acid hybridization by using intercalator binding to hybridized nucleic acid, wherein oxidation-reduction of transition metallic complex is induced to cause electrochemiluminescence, thereby providing a method for detecting nucleic acid hybridization without a special labeling.

REFERENCES:
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patent: 6221586 (2001-04-01), Barton et al.
patent: 6342359 (2002-01-01), Lee et al.
patent: 6635426 (2003-10-01), Pak et al.
patent: 6649350 (2003-11-01), Barton et al.
patent: 2002/0106682 (2002-08-01), Lee et al.
patent: 2002/0117396 (2002-08-01), Pak et al.

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