Electrochemical sensing apparatus with in situ calibration

Details Electrochemical sensing apparatus with in situ calibration Electrochemical sensing apparatus with in situ calibration

1981-03-10

1984-10-23

Padgett, Benjamin R.

Surgery

Truss

Pad

128635, A61B 500

Patent

active

044782225

ABSTRACT:
An in vivo electrochemical monitoring device is formed by a catheter-like member which terminates in a closed end having a wall with a fixed opening to admit fluid to be tested, such as blood in an artery. An electrochemical sensor, such as an ISFET device for monitoring the concentration of a particular ion in blood, is mounted inside the tube at a fixed location below the opening preferably a larger sensing chamber. an infusion channel in the tube is arranged to flood the sensor with a fluid of known chemical properties so that the sensor output can be calibrated. Under pressure the calibration fluid expels the test fluid out of the tube or chamber via the fixed opening. A method of constructing a suitable chamber on an ISFET wafer is also disclosed.

REFERENCES:
patent: 3476670 (1969-11-01), Weiner
patent: 3924321 (1975-12-01), Cook, Jr. et al.
patent: 4016866 (1977-04-01), Lawton
patent: 4020830 (1977-05-01), Johnson et al.
patent: 4041933 (1977-08-01), Reichenberger
patent: 4119406 (1978-10-01), Clemens
patent: 4120292 (1978-10-01), Le Blanc et al.
patent: 4221567 (1980-09-01), Clark et al.

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