Electrochemical immunosensor system and methods

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic

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204193, 204400, 204403, 204407, 204411, 204416, 204422, 422 8201, 422 8202, 422 8203, 435817, 4352872, 436518, 436806, G01N 33553

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054948312

ABSTRACT:
A electrochemical immunosensor system is provided which uses electrical signals to measure binding events. The system includes an immunosensor having a sensing electrode in contact with a fluid containing an analyte concentration. A quantity of antibodies or other binding agent is adsorbed on or otherwise affixed to the electrode surface such that a portion of the antibodies of the binding agent binds a portion of the analyte to form complexes on the electrode surface. Signal generating means develop an electrical signal at the sensing electrode such that a response current is produced through the sensing electrode. The response current has measurable signal characteristics which are dependent upon the number of complexes formed, and therefore the analyte concentration within the fluid.

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