Electrochemical chip with miniaturized sensor array

Chemistry: electrical and wave energy – Apparatus – Electrolytic

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C204S400000, C324S693000, C324S700000, C324S076110, C422S082010

Reexamination Certificate

active

07842174

ABSTRACT:
A handheld sensor device is provided for measuring an ion concentration in a solution. The solution is in an electrochemical cell that includes a counter electrode, a working electrode, and a reference electrode. The sensor includes a control amplifier configured to provide a current through the counter electrode and the working electrode so as to maintain a predetermined voltage between the working electrode and the reference electrode. The sensor also includes a current amplifier configured to measure the current provided through the counter electrode and the working electrode. In one embodiment, the sensor also includes a direct digital frequency synthesizer (DDFS) including a phase accumulator. The DDFS is configured to selectively generate a waveform specified by an electrochemical technique such as square wave voltammetry, cyclic voltammetry, linear sweep voltammetry, differential-pulse polarography, normal-pulse polarography, or other known electrochemical techniques. An example microelectrode array usable with the handheld sensor is also provided.

REFERENCES:
patent: 4225410 (1980-09-01), Pace
patent: 4986271 (1991-01-01), Wilkins
patent: 5063361 (1991-11-01), Smith et al.
patent: 5208646 (1993-05-01), Rogers et al.
patent: 5316633 (1994-05-01), Sakai et al.
patent: 5708687 (1998-01-01), Powell et al.
patent: 6143667 (2000-11-01), Marsh
patent: 6147851 (2000-11-01), Anderson
patent: 6906524 (2005-06-01), Chung et al.
patent: 7084641 (2006-08-01), Brederlow et al.
patent: 7189314 (2007-03-01), Pace et al.
patent: 2003/0169618 (2003-09-01), Lindsey et al.
patent: 2005/0067279 (2005-03-01), Chen et al.
patent: 2005/0112544 (2005-05-01), Xu et al.
Romero, Mario R. et al., “A Computer-Controlled Battery-Powered Micropotentiostat,” Departamento de Quimica y Fisica, Universidad Nacional de Rio Curato, Ruta 8, Km 601, 5800, Rio Curato, Argentina, Oct. 25, 1999, pp. 53-58, vol. 12, 2000 John Wiley & Sons, Inc., Lab Robotics and Automation (LRA).
Gore, Amit et al., “A Multichannel Femtoampere-Sensitivity Potentiostat Array for Biosensing Applications,” Nov. 2006, pp. 2357-2363, vol. 53, No. 11, 2006 IEEE Transactions on Circuits and Systems—I: Regular Papers, Digital Object Identifier (DOI) 10.1109/TCSI.2006.884432.
Wollenberger, U. et al., “Biosensors for analytical microsystems,” Microsystem Technologies, 1995, p. 75-83, ISSN: 0946-7076, vol. 1, Issue 2, Springer-Verlag 1995, DOI 10.1007/BF01624467.
Wittstock, Gunther, “Sensor arrays and array sensors,” Dec. 8, 2001, pp. 16-17, ISSN 1618-2642, vol. 372, Issue 1, Analytical and Bioanalytical Chemistry, Springer-Verlag 2001, DOI 10.1007/s00216-001-1149-y.
Huang, Chengjun et al., “Design and Fabrication of an Automated Microchip-Based Cell Separation Device,” 2006, pp. 763-778, vol. 40, Issue 4, Analytical Letters, Taylor & Francis Group, LLC, ISSN 0003-2719 print/1532-236X online, DOI 10.1080/00032710601017896.
Ayers, Sunitha, et al., “Design of a CMOS Potentiostat Circuit for Electrochemical Detector Arrays,” Apr. 2007, pp. 736-744, vol. 54, No. 4, 2007 IEEE Transactions on Circuits and Systems—I: Regular Papers, DOI 10.1109/TCSI.2006.888777.
Zhang, Jichun et al., “Electrochemical Array Microsystem with Integrated Potentiostat,” 2005 IEEE, pp. 385-388.
Popovtzer, Rachela et al., “Electrochemical detection of biological reactions using a novel nano-bio-chip array,” Feb. 28, 2006, pp. 664-672, 2006 Elsevier B.V., available online at www.sciencedirect.com.www.elsevier.com/locate/snb. DOI 10.1016/j.snb.2006.01.037.
Pavel, Steffan et al., “Electrochemical measurement System Based on Thick-Film Sensors,” 2006 IEEE, pp. 204-207.
Nyholm, Leif, “Electrochemical techniques for lab-on-a-chip applications,” The Royal Society of Chemistry 2005, pp. 599-605, The Analyst, www/rsc.org/analyst, DOI 10.1039/b415004j.
Ueno, Kosei et al., “Fabrication and electrochemical characterization of interdigitated nanoelectrode arrays,” Dec. 9, 2004, pp. 161-165, www.sciencedirect.com, www.elsevier.com/locate/elecom. DOI 10.1016/j.elecom.2004.12.002.
“Post-CMOS Compatible Microfabrication of a Multi-Analyte Bioelectrochemical Sensor Array Microsystem”, IEEE Sensors 2006, EXCP, Daegu, Korea—Oct. 22-25, 2006 (pp. 612-615).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Electrochemical chip with miniaturized sensor array does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electrochemical chip with miniaturized sensor array, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electrochemical chip with miniaturized sensor array will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4203106

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.