Electrochemical carboxylation of p-isobutylacetophenone

Details Electrochemical carboxylation of p-isobutylacetophenone Electrochemical carboxylation of p-isobutylacetophenone

1984-12-19

1986-04-15

Niebling, John F.

Chemistry: electrical and wave energy

Processes and products

C25B 100

Patent

active

045825777

ABSTRACT:
Hydroxyibuprofen is produced in good yield by reduction of p-isobutylacetophenone at the cathode in the presence of carbon dioxide. Hydroxyibuprofen is readily hydrogenolyzed to ibuprofen.

REFERENCES:
Wawzonek et al., J. Electrochm. Soc., vol. III, pp. 324-328 (1964).
S. Wawzonek et al. J. Electrochem. Soc., vol. 107, p. 537 (1960).
R. Engels et al., Angew. Chem. Int. Ed. Engl. 22 (1983), No. 6.
R. Engels et al., Angew. Chem. Suppl. 1983, 691-702.
"An Electrochemical Synthesis of 2-Hydroxy-2-(p-Isobutylphenyl) Propionic Acid", Chemistry Letters, The Chemical Soc. of Japan, issue No. 3, Mar. 1984, pp. 453-454.

Affiliated with

Also associated with

Rating

Electrochemical carboxylation of p-isobutylacetophenone does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electrochemical carboxylation of p-isobutylacetophenone, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electrochemical carboxylation of p-isobutylacetophenone will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1437211