Electrochemical analyte measurement system

Details Electrochemical analyte measurement system Electrochemical analyte measurement system

1999-06-16

2000-07-04

Leary, Louise N.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving glucose or galactose

435 28, 435 26, 435 24, 435288, 435291, 435817, 204403, 20415715, 2041531, 429111, 429 40, 373 80, C12Q 154, C12Q 128, C07C 100, C12M 140

Patent

active

060837101

ABSTRACT:
A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow "one-point" in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode is preferably three or four-layered, with the layers serially deposited within a recess upon the tip of a polyamide insulated gold wire. A first glucose concentration-to-current transducing layer is overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited (third layer). An outer (fourth) layer is biocompatible.

REFERENCES:
patent: 5165407 (1992-11-01), Wilson et al.
patent: 5356786 (1994-10-01), Heller et al.
patent: 5372133 (1994-12-01), Esch
patent: 5593852 (1997-01-01), Heller et al.

Affiliated with

Also associated with

Rating

Electrochemical analyte measurement system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electrochemical analyte measurement system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electrochemical analyte measurement system will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1485036