Electrocatalytic nucleic acid hybridization detection

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C536S023100, C536S024300

Reexamination Certificate

active

07361470

ABSTRACT:
The detection of specific DNA sequences using electrochemical readout would permit the rapid and inexpensive detection and identification of bacterial pathogens and the analysis of human genes. A new assay developed for this purpose is described that harnesses an electrocatalytic process to monitor DNA hybridization.

REFERENCES:
patent: 5312527 (1994-05-01), Mikkelsen et al.
patent: 5972692 (1999-10-01), Hashimoto et al.
patent: 6221586 (2001-04-01), Barton et al.
patent: 6361951 (2002-03-01), Thorp et al.
patent: 6479240 (2002-11-01), Kayyem et al.
patent: 2002/0081588 (2002-06-01), De Lumley-woodyear et al.
patent: 2003/0152960 (2003-08-01), Thorp et al.
patent: 2005/0084881 (2005-04-01), Kelley et al.
patent: 758 062 (2003-03-01), None
patent: 0 564 254 (1993-10-01), None
patent: 1629122 (2006-03-01), None
patent: 1784512 (2007-05-01), None
patent: WO 96/06946 (1996-03-01), None
patent: WO 99/67628 (1999-12-01), None
patent: WO 05/005952 (2005-10-01), None
patent: WO 06/076047 (2006-07-01), None
patent: WO 06/094200 (2006-09-01), None
patent: WO 07/094805 (2007-08-01), None
Kelley et al. Single-base mismatch detection based on charge transduction through DNA. Nucleic Acids Research 27(24) : 4830-4837 (1999).
Armistead, P.M. and Thorp, H.H. Electrochemical detection of gene expression in tumor samples: overexpression of Rak nuclear tyrosine kinase. Bioconjug Chem. Mar.-Apr. 2002;13(2):172-6.
Boon, E.M. et al., Mutation detection by electrocatalysis at DNA-modified electrodes. Nat Biotechnol. Oct. 2000;18(10):1096-100. Erratum in: Nat Biotechnol Dec. 2000;18(12):1318.
Brunetti, B et al., Electrochemistry of phenothiazine and methylviologen biosensor electron-transfer mediators at nanoelectrode ensembles. J. Electroanal. Chem. 2000; 491:166-74.
Chilvers, K.F. et al., Phototoxicity of rose bengal in mycological media—implications for laboratory practice. Lett Appl Microbiol. Feb. 1999;28(2);103-7.
Conlon, K.A. et al., Site directed photochemical disruption of the actin cytoskeleton by actin-binding Rose Bengal-conjugates. J Photochem Photobiol B. Nov. 2002;68(2-3):140-6.
Forrer, P. et al., Electrochemical preparation and surface properties of gold nanowire arrays formed by the template technique. J. Appl. Electrochem. 2000; 30:533-41.
Gooding, J.J. et al., Protein electrochemistry using aligned carbon nanotube arrays. J Am Chem Soc. Jul. 30, 2003;125(30):9006-7.
Gore, M.R. et al., Detection of attomole quantities [correction of quantitites] of DNA targets on gold microelectrodes by electrocatalytic nucleobase oxidation. Anal Chem. Dec. 1, 2003;75(23):6586-92.
Hashimoto, K. et al., Novel DNA sensor for electrochemical gene detection. Analytica Chimica Acta. Feb. 18, 1994;286(2):219-224.
Hashimoto, K. et al., Sequence-specific gene detection with a gold electrode modified with DNA probes and an electrochemically active dye. Anal Chem. Nov. 1, 1994;66(21):3830-3.
Lapierre, M.A. et al., Electrocatalytic detection of pathogenic DNA sequences and antibiotic resistance markers. Anal Chem. Nov. 15, 2003;75(22):6327-33.
Liu, S. et al., Voltammetric determination of sequence-specific DNA by electroactive intercalator on graphite electrode. Analytica Chimica Acta. Dec. 20, 1996;335(3):239-243.
Martin, C.R. an Mitchell, D.T. As particle size approaches molecular dimensions, all properties of a material change, making nanomaterials useful for particular applications. Nanomaterials in Anal Chem. May 1, 1998;322A-7A.
Menon, V.P. and Martin, C.R. Fabrication and Evaluation of Nanoelectrode Ensembles. Anal. Chem. 1995; 67:1920-8.
Millan, K.M. and Mikkelsen, S.R. Sequence-selective biosensor for DNA based on electroactive hybridization indicators. Anal Chem. Sep. 1, 1993;65(17):2317-23.
Moretto, L.M. et al., Voltammetry of redox analytes at trace concentrations with nanoelectrode ensembles. Talanta 2004; 62:1055-60.
Napier, M.E. et al., Probing biomolecule recognition with electron transfer: electrochemical sensors for DNA hybridization. Bioconjug Chem. Nov.-Dec. 1997;8(6):906-13.
Palecek, E. et al., Electrochemical biosensors for DNA hybridization and DNA damage. Biosens Bioelectron. Sep. 15, 1998;13(6):621-8.
Patolsky, F. et al., Electronic Transduction of Polymerase or Reverse Transcriptase Induced Replication Processes on Surfaces: Highly Sensitive and Specific Detection of Viral Genomes Angew Chem Int Ed Engl. Jun. 18, 2001;40(12):2261-5.
Ropp, P.A. and Thorp, H.H. Site-selective electron transfer from purines to electrocatalysts: voltammetric detection of a biologically relevant deletion in hybridized DNA duplexes. Chem Biol. Sep. 1999;6(9):599-605.
Steel, A. B. et al., Electrochemical quantitation of DNA immobilized on gold. Anal Chem. Nov. 15, 1998;70(22):4670-7.
Taft, B.J. et al., Engineering DNA-electrode connectivities: manipulation of linker length and structure. Analytica Chimica Acta. Oct. 31, 2003;496(1-2):81-91.
Thorp, H.H. Cutting out the middleman: DNA biosensors based on electrochemical oxidation. Trends in Biotechnology. 1998;16:117-121.
Vercoutere, W. and Akeson, M. Biosensors for DNA sequence detection. Curr Opin Chem Biol. Dec. 2002;6(6):816-22. Review.
Wang, J. From DNA biosenors to gene chips. Nucleic Acids Res. Aug. 15, 2000;28(16):3011-6. Review.
Xu, X.-H. et al., Immobilization of DNA on an Aluminum(III) Alkanebisphosphonate Thin Film with Electrogenerated Chemiluminescent Detection. J. Am. Chem. Soc. 1994; 116(18):8386-7.
Yu, S. et al. Nano Wheat Fields Prepared by Plasma-Etching Gold Nanowire-Containing Membranes. Nano Lett. 2004;3:815-8.
Coche-Guerente et al., Amplification of amperometric biosensor responses by electrochemical substrate recycling. 3. Theoretical and experimental study of the phenol-polyphenol oxidase system immobilized in Laponite hydrogels and layer-by-layer self-assembled structures. Anal Chem. 2001 Jul. 15;73(14):3206-18.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Electrocatalytic nucleic acid hybridization detection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electrocatalytic nucleic acid hybridization detection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electrocatalytic nucleic acid hybridization detection will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2784933

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.