Electrocatalytic asymmetric dihydroxylation of olefinic compound

Details Electrocatalytic asymmetric dihydroxylation of olefinic compound Electrocatalytic asymmetric dihydroxylation of olefinic compound

1992-02-21

1994-04-12

Niebling, John

Chemistry: electrical and wave energy

Processes and products

204 59R, 204 96, C25B 302

Patent

active

053022572

ABSTRACT:
A process is disclosed in which optically active glycols are produced through an electrolytic asymmetric dihydroxylation (ADH) reaction involving olefins as substrates. The ADH reaction is mediated by a catalytically active amount of osmium tetroxide or osmium-containing precursor in a protic medium in the presence of chiral ligand. Any lower valent osmium species produced in the course of the ADH reaction is regenerated electrolytically either directly in the absence of a secondary oxidant or indirectly in the presence of a secondary oxidant that itself undergoes electrolytic regeneration.

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