Surgery – Truss – Pad
Patent
1984-07-11
1986-03-18
Howell, Kyle L.
Surgery
Truss
Pad
128634, 128654, 128664, 128362, 128635, A61B 600, A61N 500
Patent
active
045761736
ABSTRACT:
A method and apparatus is disclosed for optically monitoring the concentration of singlet oxygen produced during photoradiation. A composite optical emission in the 1.27 micron frequency band is detected and electrically processed to separate a first component due to the decay of singlet oxygen from a second unwanted component due to the fluorescence of the photosensitizing dye.
A chopped CW excitation source is used to excite the photosensitizing dye and a signal processing means such as a lock-in amplifier is used to separate the singlet oxygen emission component which appears out of phase from the chopped excitation signal and the in-phase photosensitizer fluorescence.
The magnitude and/or other characteristics of the singlet oxygen emission component can be used to determine properties of complex biological or other media. In a therapeutic environment the magnitude and/or other characteristics of the singlet oxygen emission can be used by the treating physician to set a therapeutic light dosimetry.
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Parker John G.
Stanbro William D.
Archibald Robert E.
Califano Howard W.
Hanley John C.
Howell Kyle L.
The Johns Hopkins University
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