Electrically hydrolyzed salines as microbiocides for in vitro tr

Details Electrically hydrolyzed salines as microbiocides for in vitro tr Electrically hydrolyzed salines as microbiocides for in vitro tr

1994-07-15

1997-04-22

Rollins, John W.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

204228, 424613, 424661, 4351739, 435817, C12N 1300

Patent

active

056228481

ABSTRACT:
A microbiocidal solution for in vivo and in vitro treatment of microbial infections includes an electrolyzed saline containing regulated amounts of ozone and active chlorine species wherein the ozone content is between about 5 and 100 mg/L and the active chlorine species content of between about 5 and 300 ppm. The active chlorine species comprises free chlorine, hypochlorous acid and the hypochlorite ion as measured by a chlorine selective electrode. The solution is prepared by subjecting a 1% or less saline to electrolysis under conditions sufficient to produce the desired active ingredients. The solution is preferably utilized at an isotonic saline concentration and may be adjusted with hypertonic saline. The solution may be used for the in vitro treatment of infected whole blood, blood cells or plasma to reduce contamination and is effective in treatment of fluids infected with HIV, hepatitis and other viral, bacterial and fungal agents. The solution may also be administered to warm blooded animals, including humans, by intravenous injection or other modes for similar purposes. If desired neutralizing agents, such as antioxidants, may be administered in correlation with the solution.

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