Electric resonance chromatography

Details Electric resonance chromatography Electric resonance chromatography

1979-06-25

1980-12-09

Adee, John

Liquid purification or separation

Processes

Chromatography

2101982, B01D 1508

Patent

active

042383277

ABSTRACT:
A process and apparatus for enhancing the separation of molecules, such as cells or proteins, into distinct propulations based on their interactions with an externally imposed varying electric field during liquid gel chromatography (LGC). An electric field, at radio frequency (RF), is created between two plates of a capacitor structure and impressed through the gel media column situated between the plates. The varying field interacts with the molecules through polarization events that alter the molecular vibration and rotation motions. The induced changes cause the molecules to exhibit elution characteristics distinct from those normally obtained during LGC. Thereby, molecules can be further and more selectively partitioned according to their distinct polarization properties.

REFERENCES:
patent: 3341732 (1967-09-01), Malvin et al.
patent: 3782078 (1974-01-01), Jerpe

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