Electric modulation of sympathetic nervous system

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

10243612

ABSTRACT:
A method for the treatment of obesity or other disorders, by electrical activation or inhibition of the sympathetic nervous system. This activation or inhibition can be accomplished by electrically stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an implantable pulse generator. This nerve activation can result in reduced food intake and increased energy expenditure. Reduced food intake may occur through a variety of mechanisms that reduce appetite and cause satiety. Increased adrenal gland hormone levels will result in increased energy expenditure. Fat and carbohydrate metabolism, which are also increased by sympathetic nerve activation, will accompany the increased energy expenditure.

REFERENCES:
patent: 3911930 (1975-10-01), Hagfors et al.
patent: 4573481 (1986-03-01), Bullara
patent: 4595010 (1986-06-01), Radke
patent: 4702254 (1987-10-01), Zabara
patent: 4827935 (1989-05-01), Geddes et al.
patent: 4867164 (1989-09-01), Zabara
patent: 5095905 (1992-03-01), Klepinski
patent: 5107833 (1992-04-01), Barsness
patent: 5154172 (1992-10-01), Terry, Jr. et al.
patent: 5179950 (1993-01-01), Stanislaw
patent: 5186170 (1993-02-01), Varrichio et al.
patent: 5188104 (1993-02-01), Wernicke et al.
patent: 5205285 (1993-04-01), Baker, Jr.
patent: 5215086 (1993-06-01), Terry, Jr. et al.
patent: 5215089 (1993-06-01), Baker, Jr.
patent: 5222494 (1993-06-01), Baker, Jr.
patent: 5231988 (1993-08-01), Wernicke et al.
patent: 5235980 (1993-08-01), Varrichio et al.
patent: 5237991 (1993-08-01), Baker, Jr. et al.
patent: 5251634 (1993-10-01), Weinberg
patent: 5263480 (1993-11-01), Wernicke et al.
patent: 5269303 (1993-12-01), Wernicke et al.
patent: 5299569 (1994-04-01), Wernicke et al.
patent: 5304206 (1994-04-01), Baker, Jr. et al.
patent: 5330515 (1994-07-01), Rutecki et al.
patent: 5335657 (1994-08-01), Terry, Jr. et al.
patent: 5351394 (1994-10-01), Weinberg
patent: 5423872 (1995-06-01), Cigaina
patent: 5454840 (1995-10-01), Krakovsky et al.
patent: 5458626 (1995-10-01), Krause
patent: 5531778 (1996-07-01), Maschino et al.
patent: 5540730 (1996-07-01), Terry, Jr. et al.
patent: 5540734 (1996-07-01), Zabara
patent: 5571150 (1996-11-01), Wernicke et al.
patent: 5690691 (1997-11-01), Chen et al.
patent: 5707400 (1998-01-01), Terry, Jr. et al.
patent: 5716392 (1998-02-01), Bourgeois et al.
patent: 5725563 (1998-03-01), Klotz
patent: 5755750 (1998-05-01), Petruska et al.
patent: 5782798 (1998-07-01), Rise
patent: 5836994 (1998-11-01), Bourgeois
patent: 5919216 (1999-07-01), Houben et al.
patent: 5928272 (1999-07-01), Adkins et al.
patent: 5995872 (1999-11-01), Bourgeois
patent: 6041258 (2000-03-01), Cigaina
patent: 6068596 (2000-05-01), Weth et al.
patent: 6109269 (2000-08-01), Rise et al.
patent: 6129685 (2000-10-01), Howard, III
patent: 6146391 (2000-11-01), Cigaina
patent: 6165180 (2000-12-01), Cigaina
patent: 6169924 (2001-01-01), Meloy et al.
patent: 6308105 (2001-10-01), Duysens et al.
patent: 6321124 (2001-11-01), Cigaina
patent: 6350455 (2002-02-01), Donovan
patent: 6356786 (2002-03-01), Rezai et al.
patent: 6356787 (2002-03-01), Rezai et al.
patent: 6381495 (2002-04-01), Jenkins
patent: 6438423 (2002-08-01), Rezai et al.
patent: 6558320 (2003-05-01), Causey et al.
patent: 6587719 (2003-07-01), Barrett et al.
patent: 6721603 (2004-04-01), Zabara et al.
patent: 6885888 (2005-04-01), Rezai
patent: 2001/0014815 (2001-08-01), Matsumura et al.
patent: 2002/0072780 (2002-06-01), Foley
patent: 2002/0077675 (2002-06-01), Greenstein
patent: 2003/0018367 (2003-01-01), DiLorenzo
patent: 2003/0045909 (2003-03-01), Gross et al.
patent: 2003/0144708 (2003-07-01), Starkebaum
patent: 2004/0230255 (2004-11-01), Dobak, III
patent: 2005/0149146 (2005-07-01), Boveja et al.
patent: WO 98/57701 (1998-12-01), None
patent: WO 00/61223 (2000-10-01), None
patent: WO 01/52932 (2001-07-01), None
patent: WO 01/58520 (2001-08-01), None
patent: WO 01/83028 (2001-11-01), None
patent: WO 02/04068 (2002-01-01), None
patent: WO 02/26315 (2002-04-01), None
patent: WO 02/26317 (2002-04-01), None
patent: WO 02/34331 (2002-05-01), None
patent: WO 02/43467 (2002-06-01), None
patent: WO 02/062291 (2002-08-01), None
Buckley, N. Circulatory Effects of Splanchnic Nerve Stimulation in Developing Swine, Americal Journal of Physiology; Apr. 1984; pp. H69-H74; vol. 248.
Ahren, B.; Sympathetic Nerve Stimulation Versus Pancreatic Norepinephrine Infusion in the Dog: 1)Effects on Basal Release of Insulin Glucagon; Endocrinology; Mar. 1986; pp. 323-331; vol. 121, No. 1.
Alamo, L.; Electrically-Evoked Catecholamine Release from Cat Adrenals; Biochemical Pharmacology; Nov. 1990; pp. 973-978; vol. 42, No. 5.
Amar, Al Vagus Nerve Stimulation for Intractable Epilepsy, Cyberonics Brochure; Pub. Date unknown; thirteen pages.
Bloom, S.; The Adrenal Contribution to the Neuroendocrine Responses to Splanchnic Nerve Stimulation in Conscious Calves; Journal of Physiology; Jul. 1987; pp. 513-526; vol. 397.
Bray, G.; Reciprocal Relation of Food Intake and Sympathetic Activity: Experimental Observations and Clinical Implications; International Journal of Obesity; 2000; pp. S8-S17; vol. 24, Suppl. 2.
Brillon, D.; Effect of Cortisol on Energy Expenditure and Amino Acid Metabolism in Humans; American Journal of Physiology; May 1994; pp. E501-E513; vol. 268.
Brown, F.; Changes in Food Intake with Electrical Stimulation of the Ventromedial ypothalamus in Dogs; Journal of Neurosurgery; Jun. 1984; pp. 1253-1257; vol. 60.
Buckley, N.;Circulatory Effects of Splanchnic Nerve Stimulation in Developing Swine; American Journal of Physiology; Apr. 1984; pp. H69-H74; vol. 248.
Cigaina, V.; Long-Term Effects of Gastric Pacing to Reduce Feed Intake in Swine; Obesity Surgery; 1996; pp. 250-253; vol. 6.
Clutter, W.; Epinephrine Plasma Metabolic Clearance Rates and Physiologic Thresholds for Metabolic and Hemoduynamic Actions in Man; Journal of Clincial Investigation; Jan. 1980; pp. 94-101; vol. 66.
Cummings, D.; Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery; The New England Journal of Medicine; May 2002; pp. 1623-1630; vol. 346, No. 21.
Cuschieri, A.; Bilateral Endoscopic Splanchnicectomy through a Posterior Thorascopic Approach; J. R. Coll. Surg. Edinb.; Feb. 1994; pp. 44-47; vol. 39.
Edwards, A.; Adrenal Catecholamine Output in Responses to Stimulation of the Splanchnic Nerve in Bursts in the Conscious Calf; Journal of Physiology; Sep. 1981; pp. 409-419; vol. 327.
Edwards, A.; Adrenal Medullary Responses to Stimulation of the Splanchnic Nerve in the Conscious Calf; Journal of Physiology; Jan. 1980; pp. 15-27; vol. 308.
Edwards, A.; The Effect of Splanchnic Nerve Stimulation on Adrenocortical Activity in Conscious Calves; Journal of Physiology; Apr. 1986; pp. 385-396; vol. 382.
Edwards, A.; The Glycogenolytic Response to Stimulation of the Splanchnic Nerves in Adrenalectomized Calves, Sheep, Dogs, Cats, and Pigs; Journal of Physiology; Nov. 1970; pp. 741-759; vol. 213.
Engeland, W.; Splanchnic Nerve Stimulation Modulates Steriod Secretion in Hypophysectomized Dogs; Neuroendocrinology; Aug. 1988; pp. 124-131; vol. 50.
Furness, J.; Effects of Vagal and Splanchnic Section on Food Intake, Weight, Serum Lepin, and Hypothalamic Neuropeptide Y in Rat; Autonomic Neuroscience: Basic and Clinical; Feb. 2001; pp. 28-36; vol. 92.
Katzeff, H.; Metabolic Studies in Human Obesity during Overnutrition and Undernutrition: Thermogenic and Hormonal Responses to Norepinephrine; Metabolism; Feb. 1986; pp. 166-175; vol. 35, No. 2.
Kuo, D.; A Wide Field Electron Microscopic Analysis of the Fiber Constituents of the Major Splanchnic Nerve in Cat; The Journal of Comparative Neurology; Apr. 1982; pp. 49-58; vol. 210.
Kurose, T.; Mechanism of Sympathetic Neural Regulation of Insulin, Somatostatin, and Glucagon Secretion; American Journal of Physiology; Mar. 1989; pp. E220-E227; vol. 258.
Leibel, R.; Changes in Energy Expenditure Resulting from Altered Body Weight; The New England Journal of Medicine; Mar. 1995; pp. 621-628; vol. 332, No. 10.
Lerman, S.; Pyloric Motor Response to Sympathetic Nerve Stimulation in Dogs; Surg

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Electric modulation of sympathetic nervous system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electric modulation of sympathetic nervous system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electric modulation of sympathetic nervous system will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3754743

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.