Radiant energy – Ionic separation or analysis – Cyclically varying ion selecting field means
Reexamination Certificate
2005-02-08
2005-02-08
Wells, Nikita (Department: 2881)
Radiant energy
Ionic separation or analysis
Cyclically varying ion selecting field means
C250S282000, C250S291000, C250S287000
Reexamination Certificate
active
06852971
ABSTRACT:
In an electric charge adjusting method and mass spectrometer, tandem linear ion traps are employed such that charge-reducing reactions occur in only one of the linear ion traps. An ion reaching a given charge value is selectively moved to another linear ion trap. Through MS/MS mass analysis, the structure of a biomolecule is analyzed very efficiently with high sensitivity via a simple analysis.
REFERENCES:
patent: 4736101 (1988-04-01), Syka et al.
patent: 4755670 (1988-07-01), Syka et al.
patent: 5134286 (1992-07-01), Kelley
patent: 5783824 (1998-07-01), Baba et al.
patent: 6075244 (2000-06-01), Baba et al.
patent: RE36906 (2000-10-01), Franzen
patent: 6483109 (2002-11-01), Reinhold et al.
patent: 6515279 (2003-02-01), Baykut
patent: 20030089846 (2003-05-01), Cooks et al.
patent: WO 0115201 (2000-08-01), None
James L. Stephenson, Jr. and Scott A. McLuckey, “Ion/Ion Proton Transfer Reactions for Protein Mixture Analysis”, Anal. Chem. (Nov. 15, 1996), vol. 68, pp. 4026-4032.
James L. Stephenson, Jr. and Scott A. McLuckey, “Adaptation of the Paul Trap for Study of the Reaction of Multiply Charged Cations with Singly Charged Anions”, International Journal of Mass Spectrometry and Ion Processes (1997), pp. 89-106.
T. Gregory Schaeff, Benjamin J. Cargile, James L. Stephenson, Jr. and Scott A. McLuckey, “Ion Trap Collisional Activation of the (M+2H)2+-(M+17H)17+Ions of Human Hemoglobin β-Chain”, Analytical Chemistry, vol. 72. No. 5 (Mar. 1, 2000), pp. 899-907.
D. R. Denison, “Operating Parameters of a Quadrupole in a Grounded Cylindrical Housing”, The Journal of Vacuum Science and Technology, vol. 8, No. 1, pp. 266-269.
B. A. Collings, J.M. Campbell, Dunmin Mao and D. J. Douglas, “A Combined Linear Ion Trap Time-of-Flight System with Improved Performance and MSnCapabilities”, Rapid Communications in Mass Spectrometry (2001), vol. 15, pp. 1777-1795.
Baba Takashi
Hashimoto Yuichiro
Waki Izumi
A. Marquez, Esq. Juan Carlos
Fisher Esq. Stanley P.
Hashmi Zia R.
Hitachi , Ltd.
Reed Smith LLP
LandOfFree
Electric charge adjusting method, device therefor, and mass... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Electric charge adjusting method, device therefor, and mass..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electric charge adjusting method, device therefor, and mass... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3470698