Elastin derived composition and method of using same

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 17, 514 21, 530329, 530330, 435 681, A61K 3801, A61K 3808

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active

060691298

ABSTRACT:
The present invention is directed to a formulation or composition which is used to enhance the softness, elastin, or appearance of tissue by increasing the endogenous elastin production. Specifically, the present invention is directed to a composition formulated from the products of thermolysin digestion which are filtered through a 10,000 molecular weight cutoff device, which may be dried to have a formulation which contains 90% or greater of peptides having a molecular weight lower than 10,000 Da. This formulation is preferably applied to human skin in a cosmetic or therapeutic formulation and results in enhanced elasticity of the skin.

REFERENCES:
patent: 4327078 (1982-04-01), Charlet et al.
patent: 4474763 (1984-10-01), Lubowe
patent: 4591501 (1986-05-01), Cioca
patent: 4659740 (1987-04-01), Usher
patent: 4963656 (1990-10-01), Mitani
patent: 5017691 (1991-05-01), Lee
patent: 5079003 (1992-01-01), Scaffidi et al.
patent: 5223420 (1993-06-01), Rabaud et al.
patent: 5523291 (1996-06-01), Janzen et al.
patent: 5648209 (1997-07-01), Avrameas et al.
Hieber, A. D. et al. Detection of Elastin in the Human Fetal Membranes: Proposed Molecular Basis for Elasticity; Placenta; vol. 18; pp. 301-312; 1997.
Gibson, M. A. et al. Further Characterization of Proteins Associated with Elastic Fiber Microfibrils Including the Molecular Cloning of MAGP-2 (MP25); The Journal of Biological Chemistry; vol. 271, No. 2. pp. 1096-1103; Jan. 12, 1996.
Price, L. S. C. et al. Valyl-Alanyl-Prolyl-Glycine (VAPG) Serves as a Quantatative Marker for Human Elastins; Matrix; vol. 13. pp. 307-311; 1993.
Blankenship, J. W. et al. Oxysterol Incorporation Into Rat Aorta Resulting in Elastin Compositional Changes; Lipids; vol. 26, No. 5; pp. 381-384; 1991.
Sandberg, L. B. et al. Quantitation of Elastin in Tissues and Culture: Problems Related to the Accurate Measurement of Small Amounts of Elastin With Special Emphasis on the Rat; Connective Tissue Research; vol. 25, pp. 139-148; 1990.
Sandberg, L. et al. Structural Guidelines for an Acceptable Elastin and Tropoelastin: Application Towards Quantitation of Elastin Accumulation in Tissue Culture; Elastin: Chemical and Biological Aspects (Reprinted); pp. 24-44; 1990.
Sandberg, L. B. et al. Quantitation of Elastin Through Measurement of Its Pentapeptide Content; Biochemical and Biophysical Research Communications; vol. 136, No. 2. pp. 672-678; Apr. 29, 1986.
Database CaPlus, AN 108:167920. Bayer et al. Z. Naturforsch., C: Biosci, 42(4), 455-60), Apr. 1987.
Hunninghake et al. Science, 212, 925-927, May 1981.
Database Caplus, DN 127:219499. Morrelli et al. J. Pept. Res., 49 (6), 429-499, Jun. 1997.
Database Caplus, DN 122:102414. Bisaccia et al. Int, J. Pept. Res, 44, 332-341, Apr. 1994.

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