Compositions: coating or plastic – Coating or plastic compositions – Dental
Patent
1997-07-17
1999-07-20
Kaslow, Melissa
Compositions: coating or plastic
Coating or plastic compositions
Dental
523115, 523116, 523117, 4332281, 526335, 524436, A61K 600, A61K 4904, A61C 504, A61C 2700
Patent
active
059251794
DESCRIPTION:
BRIEF SUMMARY
The present invention relates to an elastic-plastic element comprising an isoprene-based matrix and at least one filler, the element being suitable for filling root canals of humans or animals. The invention relates also to a method of preparing the elastic-plastic element.
In the treatment of the disorder known as pulpitis, the diseased pulpa is removed mechanically from the root canal and the root canal is cleaned and drilled out, filled with an elastic-plastic element or with a different filling material and then sealed. For the prior art, see, for example, Friedman et al. in J. Dent. Res., 54 (1975) 921-925, Briseno in Philipp J. 2.98 (1990) and U.S. Pat. No. 4,632,977. As root canal filling materials, Briseno describes, inter alia, semi-rigid cements based on synthetic resin, zinc oxide eugenol or on calcium hydroxide. U.S. Pat. No. 4,632,977 proposes filling materials based on trans-polyisoprene, for example based on gutta-percha or balata. Gutta-percha points are commercially available, the standard composition thereof being 20% by weight of gutta-percha as matrix, from 60 to 75% by weight of zinc oxide as filler, from 1 to 17% by weight of heavy metal sulphates as X-ray contrast agent and from 3 to 4% by weight of waxes and resins as plasticizer. That known filling material is inert in the root canal and accordingly does not react with body tissue.
During the filling of a root canal with a known inert filling material, it cannot, however, be ruled out that, for example as a result of germs remaining in the canal, after the filling operation an inflammatory process may slowly develop which renders further treatment necessary, often resulting in complete loss of the tooth.
In view of the prior art, the problem underlying the present invention is to provide an elastic-plastic element for filling root canals of humans or animals that can be prepared and processed readily and simply and is not subject to the adverse effects mentioned. The problem underlying the present invention is also to provide a method of preparing such an element.
That problem is solved according to an embodiment of the invention by an elastic-plastic element comprising an isoprene-based matrix and at least one filler, the element being suitable for filling root canals of humans or animals and being characterised by calcium hydroxide, incorporated into the matrix, as filler.
Calcium hydroxide can be processed readily with an isoprene-based matrix, such as gutta-percha, it being advantageous to roll in the calcium hydroxide in the form of a powder, which simplifies the preparation process substantially.
Since calcium hydroxide has an alkaline action, it is able to buffer the acids that form in inflammatory processes and is able to limit a rise in the pH value. As a result, the healing process is advantageously accelerated and assisted. The insert can remain in the root canal temporarily or for a prolonged period of time.
According to the invention, a matrix based on trans-polyisoprene, gutta-percha and/or on balata may be provided. The matrix may be characterised by at least 80% by weight of trans-polyisoprene.
The elastic-plastic element according to the invention may be in the form of a gutta-percha point.
The calcium hydroxide used as filler according to the invention may be provided in the form of a mixture with a customary, different filler, such as zinc oxide, or may be provided as sole filler. The filler is preferably more of calcium silicate.
Of course, the elastic-plastic element according to the invention may comprise additionally a pharmaceutical active ingredient, especially an active ingredient that is soluble or dispersible in an aqueous medium, for example an antibiotic and/or glucocorticoid, and also a customary X-ray contrast agent and customary waxes, resins or other excipients. An elastic-plastic element according to the invention may be characterised preferably by: based on (a) and (b), and
For example, the elastic-plastic element according to the invention may be characterised, for example, by filler, based on (
REFERENCES:
patent: 4483678 (1984-11-01), Fujisawa et al.
patent: 4632977 (1986-12-01), Riazi
patent: 4657592 (1987-04-01), Takubo
patent: 4740245 (1988-04-01), Futami et al.
patent: 5540766 (1996-07-01), Castellani
patent: 5648403 (1997-07-01), Martin
Briseno, "Die Thermoplastischen Wurzelkanalfullmethoden im Uberblick", Philipp J., vol. 2 (90), pp. 65-73, 1990 no month.
Friedman et al., "Composition and Mechanical Properties of Gutta-Percha Endodontic Points," Journal of Dental Research, vol. 54, No. 5, (Sep.-Oct., 1975) pp. 921-925.
Kaslow Melissa
Roeko GmbH & Co., Dentalerzeugnisse
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