Eimeria tenella polypeptide and vaccine containing same

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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4241841, 4241851, 4242711, 530350, 435 691, 435 693, A61K 3900, A61K 39012, C12P 2106

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active

058143203

ABSTRACT:
The invention is concerned with a protein having the immunological properties of Eimeria tenella which is reactive with a monoclonal antibody E. TEN 11P-2 raised against E. tenella sporozoites.
The invention also relates to polypeptide fragments of this protein which can be used for immunization against E. tenella. These proteins and polypeptides can be prepared by isolation from E. tenella, by chemical synthesis or by recombinant DNA methods using the polynucleotides described herein or related sequences.

REFERENCES:
patent: 4639372 (1987-01-01), Murray et al.
patent: 4650676 (1987-03-01), Schenkel et al.
patent: 4710377 (1987-12-01), Schenkel et al.
patent: 5279960 (1994-01-01), Anderson et al.
L.E. Clarke et al., Molecular and Biochemical Parasitology, 22 (1987) 79-87.
M.C. Jenkins et al., Experimental Parasitology, 66:96-107 (1988).

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