Ehrlichia species from a patient suffering from ehrlichiosis

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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4352402, 435243, 435260, C12N 100, C12N 120, C12N 500

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active

054139317

ABSTRACT:
A new isolate of Ehrlichia species has been obtained from a patient suffering from ehrlichiosis. The new isolate has been found to be similar, but distinctly different from E. canis. The new isolate is E. chaffeensis and is contained in a cell line of canine macrophage cells on deposit with the American Type Culture Collection under accession number CRL 10679. The new isolate must be contained in a cell line in order to remain viable but may be isolated from the cell line. However, the isolate will not remain viable outside of the cell line. A diagnostic kit and methods for diagnosing ehrlichiosis in humans and for screening drugs toxic to the new isolate have also been desclosed.

REFERENCES:
Dumler et al. "Human Ehrlichiosis", Current Sci., pp. 597-602, 1991.

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