Ehrlichia canis genes and vaccines

Details Ehrlichia canis genes and vaccines Ehrlichia canis genes and vaccines

2011-05-31

2011-05-31

Paras, Jr., Peter (Department: 1632)

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

C424S009200, C435S320100, C536S023100, C514S04400A

Reexamination Certificate

active

07951386

ABSTRACT:
This invention provides the sequence of 5,299 nucleotides from theE. canisgenome. There are four proteins, ProA, ProB, MmpA, and a cytochrome oxidase homolog, as well as a partial lipoprotein signal peptidase homolog at the carboxy terminus, coded for in this cloned fragment. The antigenic properties of these proteins allow them to be used to create a vaccine. An embodiment of this invention includes the creation of a DNA vaccine, a recombinant vaccine, and a T cell epitope vaccine. Another embodiment of this invention includes the use of serological diagnosis techniques.

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