Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Patent
1989-03-01
1993-06-08
Hill, Jr., Robert J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
435 691, 435 701, A61K 3736, A61K 3710, C12P 2106
Patent
active
052180930
ABSTRACT:
Biologically active variants of epidermal growth factor are provided, comprising tandemly linked units of monomeric EGF. The variants are useful per se as therapeutic agents to promote wound healing. Production of the multimeric EGF by genetically engineered microbial hosts is also described.
REFERENCES:
patent: 4764593 (1988-08-01), Banks et al.
patent: 4783524 (1988-11-01), Larsen et al.
Guo Zimin
Sills A. Michael
Skipper Nigel A.
Allelix Biopharmaceuticals Inc.
Guest Shelly J.
Hill Jr. Robert J.
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