Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-05-30
2006-05-30
Wilson, James O. (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C424S009362, C424S009610, C534S015000, C514S185000, C514S410000
Reexamination Certificate
active
07053210
ABSTRACT:
A process for the preparation of pyropheophorbide a and its derivatives, including 3-devinyl-3-(1′-hexyloxy)ethyl-pyropheophorbide-a, otherwise known as HPPH, is provided. The process involves treating chlorin e6, in the form of its trimethyl ester, with a base, followed by heating to give pyropheophorbide a, which is converted to HPPH by treatment with acid, followed by hexyl alcohol under basic conditions.
REFERENCES:
patent: 3710795 (1973-01-01), Higuchi et al.
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3927193 (1975-12-01), Hansen et al.
patent: RE28819 (1976-05-01), Thompson
patent: 4044126 (1977-08-01), Cook et al.
patent: 4328245 (1982-05-01), Yu et al.
patent: 4331647 (1982-05-01), Goldenberg
patent: 4348376 (1982-09-01), Goldenberg
patent: 4358603 (1982-11-01), Yu
patent: 4361544 (1982-11-01), Goldenberg
patent: 4364923 (1982-12-01), Cook et al.
patent: 4374925 (1983-02-01), Litman et al.
patent: 4409239 (1983-10-01), Yu
patent: 4410545 (1983-10-01), Yu et al.
patent: 4414209 (1983-11-01), Cook et al.
patent: 4444744 (1984-04-01), Goldenberg
patent: 4468457 (1984-08-01), Goldenberg et al.
patent: 4474893 (1984-10-01), Reading
patent: 4479895 (1984-10-01), Auditore-Hargreaves
patent: 4521762 (1985-06-01), Kapral
patent: 4522811 (1985-06-01), Eppstein et al.
patent: 4577636 (1986-03-01), Spears
patent: 4624846 (1986-11-01), Goldenberg
patent: 4649151 (1987-03-01), Dougherty et al.
patent: 4656186 (1987-04-01), Bommer et al.
patent: 4675338 (1987-06-01), Bommer et al.
patent: 4693885 (1987-09-01), Bommer et al.
patent: 4753958 (1988-06-01), Weinstein et al.
patent: 4818709 (1989-04-01), Primus et al.
patent: 4861876 (1989-08-01), Kessel
patent: 4866168 (1989-09-01), Dougherty et al.
patent: 4878891 (1989-11-01), Judy et al.
patent: 4889129 (1989-12-01), Dougherty et al.
patent: 4916221 (1990-04-01), Kumadaki et al.
patent: 4925736 (1990-05-01), Shikowitz
patent: 4932934 (1990-06-01), Dougherty et al.
patent: 4935498 (1990-06-01), Sessler et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 4957481 (1990-09-01), Gatenby
patent: 4968715 (1990-11-01), Dougherty et al.
patent: 4997639 (1991-03-01), Aizawa et al.
patent: 5002962 (1991-03-01), Pandey et al.
patent: 5004811 (1991-04-01), Bommer et al.
patent: 5015463 (1991-05-01), Dougherty et al.
patent: 5028594 (1991-07-01), Carson
patent: 5028621 (1991-07-01), Dougherty et al.
patent: 5033252 (1991-07-01), Carter
patent: 5041078 (1991-08-01), Matthes et al.
patent: 5051415 (1991-09-01), Moran et al.
patent: 5052558 (1991-10-01), Carter
patent: 5053006 (1991-10-01), Watson
patent: 5059415 (1991-10-01), Neuwelt
patent: 5062431 (1991-11-01), Potter
patent: 5066274 (1991-11-01), Bommer et al.
patent: 5066291 (1991-11-01), Stewart
patent: 5074632 (1991-12-01), Potter
patent: 5093349 (1992-03-01), Pandey et al.
patent: 5095030 (1992-03-01), Levy et al.
patent: 5111821 (1992-05-01), Potter
patent: 5145863 (1992-09-01), Dougherty et al.
patent: 5171741 (1992-12-01), Dougherty
patent: 5173504 (1992-12-01), Dougherty
patent: 5190536 (1993-03-01), Wood et al.
patent: 5190966 (1993-03-01), Dougherty et al.
patent: 5198460 (1993-03-01), Pandey et al.
patent: 5205291 (1993-04-01), Potter
patent: 5216012 (1993-06-01), Morgan et al.
patent: 5219345 (1993-06-01), Potter
patent: 5222795 (1993-06-01), Hed
patent: 5225433 (1993-07-01), Dougherty et al.
patent: 5257970 (1993-11-01), Dougherty
patent: 5263925 (1993-11-01), Gilmore, Jr. et al.
patent: 5298018 (1994-03-01), Narciso, Jr.
patent: 5308861 (1994-05-01), Aizawa et al.
patent: 5314905 (1994-05-01), Pandey et al.
patent: 5323907 (1994-06-01), Kalvelage
patent: 5330741 (1994-07-01), Smith et al.
patent: 5344928 (1994-09-01), Masuya et al.
patent: 5368841 (1994-11-01), Trauner et al.
patent: 5403308 (1995-04-01), Wood et al.
patent: 5418130 (1995-05-01), Platz et al.
patent: 5430051 (1995-07-01), Aizawa et al.
patent: 5441531 (1995-08-01), Zarate et al.
patent: 5459159 (1995-10-01), Pandey et al.
patent: 5482698 (1996-01-01), Griffiths
patent: 5484803 (1996-01-01), Richter
patent: 5496308 (1996-03-01), Brown et al.
patent: 5498710 (1996-03-01), Pandey et al.
patent: 5500009 (1996-03-01), Mendes et al.
patent: 5503637 (1996-04-01), Kyricos et al.
patent: 5506255 (1996-04-01), Smith et al.
patent: 5514669 (1996-05-01), Selman
patent: 5525338 (1996-06-01), Goldenberg
patent: 5532171 (1996-07-01), Motsenbocker
patent: 5534506 (1996-07-01), Morgan et al.
patent: 5538945 (1996-07-01), Pallenberg et al.
patent: 5549660 (1996-08-01), Mendes et al.
patent: 5556612 (1996-09-01), Anderson et al.
patent: 5567409 (1996-10-01), Aizawa et al.
patent: 5571152 (1996-11-01), Chen et al.
patent: 5580896 (1996-12-01), Horwell et al.
patent: 5591847 (1997-01-01), Pandey et al.
patent: 5594136 (1997-01-01), Sessler et al.
patent: 5599923 (1997-02-01), Sessler et al.
patent: 5622983 (1997-04-01), Horwell et al.
patent: 5624798 (1997-04-01), Yamamoto et al.
patent: 5631281 (1997-05-01), Horwell et al.
patent: 5637311 (1997-06-01), Pallenberg
patent: 5648485 (1997-07-01), Dolphin et al.
patent: 5665328 (1997-09-01), Horan et al.
patent: 5671317 (1997-09-01), Weishaupt et al.
patent: 5688486 (1997-11-01), Watson et al.
patent: 5697902 (1997-12-01), Goldenberg
patent: 5698405 (1997-12-01), Goldenberg
patent: 5702432 (1997-12-01), Chen et al.
patent: 5703230 (1997-12-01), Boyle et al.
patent: 5705518 (1998-01-01), Richter et al.
patent: 5709874 (1998-01-01), Hanson et al.
patent: 5715837 (1998-02-01), Chen
patent: 5716595 (1998-02-01), Goldenberg
patent: 5736563 (1998-04-01), Richter
patent: 5741316 (1998-04-01), Chen et al.
patent: 5759542 (1998-06-01), Gurewich
patent: 5766234 (1998-06-01), Chen et al.
patent: 5770619 (1998-06-01), Richter et al.
patent: 5770730 (1998-06-01), Pandey et al.
patent: 5773977 (1998-06-01), Dougherty
patent: 5776093 (1998-07-01), Goldenberg
patent: 5776094 (1998-07-01), Goldenberg
patent: 5776095 (1998-07-01), Goldenberg
patent: 5782896 (1998-07-01), Chen et al.
patent: 5800478 (1998-09-01), Chen et al.
patent: 5814008 (1998-09-01), Chen et al.
patent: 5824080 (1998-10-01), Lamuraglia
patent: 5827186 (1998-10-01), Chen et al.
patent: 5829448 (1998-11-01), Fisher et al.
patent: 5831088 (1998-11-01), Dolphin et al.
patent: 5832931 (1998-11-01), Wachter et al.
patent: 5840674 (1998-11-01), Yatvin et al.
patent: 5851225 (1998-12-01), Lawandy
patent: 5860957 (1999-01-01), Jacobsen et al.
patent: 5864035 (1999-01-01), Pandey et al.
patent: 5865840 (1999-02-01), Chen
patent: 5876427 (1999-03-01), Chen et al.
patent: 5885557 (1999-03-01), Lentini
patent: 5886173 (1999-03-01), Hemmi et al.
patent: 5900252 (1999-05-01), Calanchi et al.
patent: 5913884 (1999-06-01), Trauner et al.
patent: 5921244 (1999-07-01), Chen et al.
patent: 5942534 (1999-08-01), Trauner et al.
patent: 5944748 (1999-08-01), Mager et al.
patent: 5945762 (1999-08-01), Chen et al.
patent: 5948433 (1999-09-01), Burton et al.
patent: 5952366 (1999-09-01), Pandey et al.
patent: 5957960 (1999-09-01), Chen et al.
patent: 5972366 (1999-10-01), Haynes et al.
patent: 5976535 (1999-11-01), Fritzberg et al.
patent: 5983134 (1999-11-01), Ostrow
patent: 5985307 (1999-11-01), Hanson et al.
patent: 5985317 (1999-11-01), Venkateshwaran et al.
patent: 5997569 (1999-12-01), Chen et al.
patent: 5997842 (1999-12-01), Chen
patent: 5998597 (1999-12-01), Fisher et al.
patent: 6004534 (1999-12-01), Langer et al.
patent: 6010715 (2000-01-01), Wick et al.
patent: 6015897 (2000-01-01), Theodore et al.
patent: 6017888 (2000-01-01), Pallenberg et al.
patent: 6022961 (2000-02-01), Yamamoto et al.
patent: 6024975 (2000-02-01), D'Angelo et al.
patent: 6028099 (2000-02-01), de Juan, Jr.
patent: 6036941 (2000-03-01), Bottiroli et al.
patent: 6039975 (2000-03-01), Shah et al.
patent: 6048359 (2000-04-01), Biel
patent: 6048736 (2000-04-01), Kosak
patent: 6051207 (2000-04-01), Klaveness et al.
patent: 6051702 (2000-04-01), Bird et al.
patent: 6060082 (2000-05-01), Chen et al.
patent: 6063108 (2000-05-01), Salansky et al.
patent: 6063777 (2000-05-01), Hikida et al.
patent: 6071495 (2000-06-01), Unger et al.
patent: 6080160 (2000-06-01), Ch
Dougherty Thomas J.
Pallenberg Alexander J.
Pandey Ravindra K.
Dunn Michael L.
Fedowitz Mathew L.
Health Research , Inc.
Wilson James O.
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