Efficient stereoconservative synthesis of 1-substituted (S)- and

Details Efficient stereoconservative synthesis of 1-substituted (S)- and Efficient stereoconservative synthesis of 1-substituted (S)- and

1992-11-12

1994-04-05

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20709

Patent

active

053006607

ABSTRACT:
Stereoconservative method for preparation of an (R)- or (S)-isomer of the compound of the formula I with at least 95% optical purity ##STR1## wherein R.sup.1 is a hydrogen atom, a saturated or unsaturated lower alkyl group, a cycloalkyl group, or a group (CH.sub.2).sub.m Ph wherein m is 0-3 and Ph is a substituted or unsubstituted phenyl group including

REFERENCES:
Moragues et al, J. C. S. Perkins Trans. I, (1976) pp. 938-940.
Knefeli et al, Arch. Pharm., pp. 773-781 (1983).

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