Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-09-06
2005-09-06
Leffers, Gerry (Department: 1636)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S320100, C435S069100, C435S325000, C435S471000, C435S348000, C435S419000, C530S350000, C530S387300
Reexamination Certificate
active
06939959
ABSTRACT:
Nucleic acid expression control sequence cassettes and vectors containing the same are provided for use in making abundant quantities of recombinant polypeptides of interest. The modified transcriptional control sequences, which include a T5 promoter sequence, are highly stable and can be used in a variety of vectors, such as plasmids.
REFERENCES:
patent: 4495280 (1985-01-01), Bujard et al.
patent: 4868111 (1989-09-01), Bujard et al.
patent: 5350690 (1994-09-01), Zukowski
patent: 5689056 (1997-11-01), Cramer et al.
patent: 5756347 (1998-05-01), Sugimoto et al.
patent: 5876962 (1999-03-01), Bishop et al.
patent: 5985285 (1999-11-01), Titball et al.
patent: 6063386 (2000-05-01), Dale et al.
patent: 6194168 (2001-02-01), Gentz et al.
patent: 6291245 (2001-09-01), Kopetzki et al.
patent: 6436639 (2002-08-01), Kiefer et al.
patent: WO 94/06465 (1994-06-01), None
patent: WO 99/16858 (1999-04-01), None
NCBI sequence viewer, J01636,E. colilactose operator sequence, date available May 5, 1993, NCBI, pp. 1-10 accessed on Nov. 8, 2004.
Novagen Catalog pET-24a-d(+) Vector, TB070, Dec. 1998.
Briat, J.-F. et al., “Identification and characterization of a new transcriptional termination factor fromEscherichia coli,” Proc. Natl. Acad. Sci. USA 81:7373-7377, Dec. 1984.
Brosius, J. et al., “Gene Organization and Primary Structure of a Ribosomal RNA Operon fromEscherichia coli,” J. Mol. Biol. 148(2): 107-127, May 15, 1981.
Casadaban, M.J. et al., “Analysis of Gene Control Signals by DNA Fusion and Cloning inEscherichia coli,” J. Mol. Biol. 138(2): 179-207, Apr. 5, 1980.
De Boer, H.A. et al., “A Hybrid Promoter and Portable Shine-Dalgarno Regions ofEscherichia coli,” Biochem. Soc. Symp. 48:233-244, 1983.
Dunn, J.J. et al., “The transcription termination site at the end of the early region of bacteriophage T7 DNA,”Nucleic Acids Research 8(10): 2119-2132, May 24, 1980.
Ehrlich, S.D. et al., “DNA cloning inBacillus subtilis,” Proc. Natl. Acad. Sci. USA 75(3): 1433-1436, Mar. 1978.
Gilman, M.Z. et al., “Nucleotide sequence of twoBacillus subtilispromoters used byBacillus subtilissigma-28 RNA polymerase,”Nucleic Acids Research 9(2): 5991-6000, 1981.
Grange, T. et al., “Expression of the mouse dihydrofolate reductase cDNA inB. subtilis:a system to select mutant cDNAs coding for methotrexate resistant enzymes,”Nucleic Acids Research 12(8): 3583-3601, 1984.
Gryczan, T.J. et al., “Characterization ofStaphylococcus aureusPlasmids Introduced by Transformation intoBacillus subtilis,” Journal of Bacteriology 134(1): 318-329, Apr. 1978.
Hawley, D.K. et al., “Compilation and analysis ofEscherichia colipromoter sequences,”Nucleic Acids Research 11(8): 2237-2255, 1983.
Jay, E. et al., “High-level expression of a chemically synthesized gene for human interferon-γ using a prokaryotic expression vector,”Proc. Natl. Acad. Sci. USA 81(8): 2290-2294, Apr. 1984.
Kreft, J. et al., “Recombinant Plasmids Capable of Replication inB. subtilisandE. coli,” Molec. gen. Genet. 162:59-67, 1978.
Lee, G. et al., “Nucleotide Sequence of a Promoter Recognized byBacillus subtilisRNA Polymerase,”Molec. gen. Genet. 180(1): 57-65, 1980.
Lee, G. et al., “Transcription of Clonded DNA fromBacillus subtilisPhage SP01 Requirement for Hydroxymethyluracil-containing DNA by Phage-modified RNA polymerase,”J. Mol. Biol. 139(3): 407-422, May 25, 1980.
McLaughlin, J.R. et al., “Unique Features in the Ribosome Binding Site Sequence of the Gram-positiveStaphylococcus aureusβ-Lactamase Gene,”The Journal of Biological Chemistry 256(21): 11283-11291, Nov. 10, 1981.
Michel, B. et al., “DNA cloning inBacillus subtilis.III. Efficiency of random-segment cloning and insertional inactivation vectors,”Gene 12:147-154, 1980.
Moran, C.P. et al., “Nucleotide sequence ofBacillus subtilispromoter recognized byBacillus subtilisRNA polymerase containing σ37,”Nucleic Acids Research 9(22): 5979-5990, 1981.
Moran, C.P. et al., “Nucleotide Sequences that Signal the Initiation of Transcription and Translation inBacillus subtilis,” Molec. gen. Genet. 186(3): 339-346, 1982.
Moran, C.P. et al., “Promoter for a Developmentally Regulated Gene inBacillus subtilis,” Cell 25(3): 783-791, Sep. 1981.
Murray, C.L. et al., “Nucleotide Sequences of Transcription and Translation Initiation Regions in Bacillus phage φ29 Early Genes,”The Journal of Biological Chemistry 257(2): 1053-1062, Jan. 25, 1982.
Nunberg, J.H. et al., “Structure and Genomic Organization of the Mouse Dihydrofolate Reductase Gene,”Cell 19(2): 355-364, Feb. 1980.
Rosenberg, M. et al., “Determination of nucleotide sequences beyond the sites of transcriptional termination,”Proc. Natl. Acad. Sci. USA 73(3): 717-721, Mar. 1976.
Schoner, R. et al., “Enhanced expression of mouse dihydrofolate reductase inBacillus subtilis,” Gene 22:47-57, 1983.
Simons, G. et al., “High-level expression of human interferon gamma inEscherichia coliunder control of the pLpromoter of bacteriophage lambda,”Gene 28:55-64, 1984.
Stüber, D. et al., “Electron Microscopic Analysis of in vitro Transcriptional Complexes: Mapping of Promoters of the Coliphage T5 Genome,”Molec. gen. Genet. 166(2): 141-149, 1978.
Stüber, D. et al., “Organization to transcriptional signals in plasmids pBR322 and pACYC184,”Proc. Natl. Acad. Sci. USA 78(1): 167-171, Jan. 1981.
Stueber, D. et al., “A novel in vitro transcription-translation system: accurate and efficient synthesis of single proteins from cloned DNA sequences,”The EMBO Journal 3(13): 3143-3148, Dec. 1984.
von Gabain, A. et al., “Interaction ofEscherichia coliRNA polymerase with promoters of several coliphage and plasmid DNAs,”Proc. Natl. Acad. Sci. USA 76(1): 189-193, Jan. 1979.
West, R.W. et al., “Construction and Characterization ofE. coliPromoter-Probe Plasmid Vectors. II. RNA Polymerase Binding Sites on Antibiotic-Resistance Promoters,”Gene 9(3/4): 175-193, May 1980.
Zukowski, M.M. et al., “Chromogenic identifications of genetic regulatory signals inBacillus subtilisbased on expression of Pseudomonas gene,”Proc. Natl. Acad. Sci. USA 80(4): 1101-1105, Feb. 1983.
ID Biomedical Corporation of Washington
Leffers Gerry
Marvich Maria
LandOfFree
Efficient protein expression system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Efficient protein expression system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Efficient protein expression system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3427747