Efficient process for the preparation of cabergoline and its...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C546S067000

Reexamination Certificate

active

07939665

ABSTRACT:
This invention relates to a new and efficient process for the production of dopamine agonists such as Cabergoline and the intermediates thereof.

REFERENCES:
patent: 4166182 (1979-08-01), Kornfeld et al.
patent: 4526892 (1985-07-01), Salvati et al.
patent: 5382669 (1995-01-01), Candiani et al.
patent: 5705510 (1998-01-01), DeSantis, Jr. et al.
patent: 6696568 (2004-02-01), Gutman et al.
patent: 1156648 (1983-11-01), None
patent: 2412861 (2002-10-01), None
patent: 287 176 (1999-04-01), None
patent: 0040325 (1981-11-01), None
patent: 2103603 (1983-02-01), None
patent: WO 95/05176 (1995-02-01), None
patent: WO 99/36095 (1999-07-01), None
patent: WO 99/48484 (1999-09-01), None
patent: WO 02/085902 (2002-10-01), None
patent: WO 2006/097345 (2006-09-01), None
patent: WO2007/091039 (2007-08-01), None
Carlsen, et al.; A greatly improved procedure for ruthenium tetraoxide catalyzed oxidations of organic compounds.; J. of Organic Chemistry; 1981;46:3936-3938.
Brambilla, et al.; Synthesis and nidation inhibitory activity of a new class of ergoline derivatives.; European J. of Medicinal Chemistry; 1989;24:421-426.
Russo, et al.; Mild, efficient trimethylaluminum-mediated cyclopropanations . . . acid.; J. Org. Chem. 1993:3589-3590.
Davis, et al.; Selective oxidation of monosaccharide derivatives to uronic acids.; Tetrahedron Lett.; 1993;34(7):1181-1184.
Mickel, et al.; Large-scale synthesis of the anti-cancer . . . fragment C7-24.; Organic Process Res. and Dev.; 2004;8:113-121.
Crombie, et al.; Synthesis and configuration of (+)-6-methyloctanic acid, a degradation product of the polymyxins.; J. of the Chem. Soc.; 1950; part III:2685-2689.
Rajashekhar, et al.; Synthesis of enantiomerically pure gamma-amino-beta-hydroxybutyric acid using mallic acid as the chiral precursor.; J. Org. Chem.; 1985;50:5480-5484.
Barak, et al.; Selective oxidation of alcohols by . . . conditions.; J. Org. Chem.;1988;53:3553-3555.
Marino, et al.; Regio and stereoselectivity of the reaction between . . . prostaglandins.; J. Org. Chem.;1987;52:4898-4913.
Sznaidman, et al.; Carbohydrate cyclic ketene acetals.; J. of Org. Chem.;1995;60:3942-3943.
McCamley, et al.; Efficient n-demethylation of opiate alkaloids using a modified nonclassical Polovski reaction.; J. of Org. Chem.;2003;68:9847-9850.
Narog, et al.; Iron(II, III)-catalyzed oxidative . . . dioxygen.; J. of Molecular Catalysis;2004;Chem 212:25-33.
Braun, et al.; German article; Chemische Berichte;1909:2035-2057.
Mantegani, et al.; Synthesis of tritium and carbon . . . prolactin lowering agent.; J. of Labelled Compounds and Radiopharmaceuticals;1991:519-533.
Ashford, et al.; A practical synthesis of cabergoline.; J. of Organic Chemistry;2002;67:7147-7150.
Candiani, et al.; The ligand effect in copper(I)-catalyzed chemoselective amide carbamoylation in cabergoline synthesis.; Synthesis Letters;1995:605-606.
Chong, et al.; Nucleophilic openings of 2,3-epoxy acids and amides mediated by . . . selectivity.; J. of Organic Chemistry;1985;50:1560-1563.
Grierson; The Polonovski reaction.; Organic Reactions;1990;ch 2;39:85-295.
Greene, et al.; Protection for the amino group.; Protective Groups in Organic Synthesis;1999;ch 7:503-653.

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