Efficient photochemical formation of 1-.alpha.-hydroxyprevitamin

Details Efficient photochemical formation of 1-.alpha.-hydroxyprevitamin Efficient photochemical formation of 1-.alpha.-hydroxyprevitamin

1982-08-30

1984-12-25

Williams, Howard S.

Chemistry: electrical and wave energy

Processes and products

Processes of treating materials by wave energy

B01J 1912

Patent

active

044902263

ABSTRACT:
An improved method is set out for converting a reactant having a reactant core portion, 5,7-androstadiene-1.alpha.,3.beta.-diol, into a product having a product core portion, 9,10-seco-5(10),6,8-androstatriene-1.alpha.,3.beta.-diol. The core portions have a group, R, attached at the 17 position wherein R is any group which does not significantly effect the absorption characteristics of the reactant core portion in a range from about 280 nm to about 310 nm. The reaction is carried out by irradiating the reactant with radiation restricted substantially solely to be in the range from about 280 nm to about 310 nm. The improvement of the invention comprises maintaining the temperature of the reactant, during the irradiating, below about 0.degree. C. and controlling the total doses of radiation to be such that (1) undesirable byproducts are not produced in an amount of more than about 15% and (2) at least about 60% of the product is produced based upon the quantity of the reactant consumed. The method gives yields of at least double that obtainable with prior art methods.

REFERENCES:
patent: 1904751 (1933-04-01), Reerink et al.
patent: 4001096 (1977-01-01), Salmond

Affiliated with

Also associated with

Rating

Efficient photochemical formation of 1-.alpha.-hydroxyprevitamin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Efficient photochemical formation of 1-.alpha.-hydroxyprevitamin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Efficient photochemical formation of 1-.alpha.-hydroxyprevitamin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1151562