Efficient construction of gene targeting vectors

Details Efficient construction of gene targeting vectors Efficient construction of gene targeting vectors

1997-10-31

2000-07-18

Ketter, James

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

4351723, C12Q 168

Patent

active

060905549

ABSTRACT:
The present invention is directed to methods for producing or obtaining gene targeting constructs by way of homologous recombination in host cells and to targeting constructs produced by those methods. The invention is also directed to transgenic animals having targeted mutations introduced in to the cells of the animal using the targeting constructs of the invention.

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