Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Patent
1997-10-31
2000-07-18
Ketter, James
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
435477, 4352351, C12N 1564
Patent
active
060906294
ABSTRACT:
A method for producing gene targeting constructs in bacterial by way of homologous recombination between bacterial phage and plasmids.
REFERENCES:
patent: 4710465 (1987-12-01), Weissman et al.
patent: 5530178 (1996-06-01), Mak
patent: 5625122 (1997-04-01), Mak
Tsuzuki et al., "Embryonic stem cell gene targeting using bacteriophage lambda vectros generated by phage-plasmid recombination", Nuclei Acid Res., vol. 26(4):988-993 (Feb. 15, 1998).
International Search Report dated Oct. 2, 1998, International Appl. No. PCT/US98/11151.
Ausubel et al., (Eds.), in Current Protocols in Molecular Biology, Chapter 5, "Construction of Recombinant DNA Libraries," John Wiley & Sons, Inc. p. 5.0.1-5.11.2 (1987).
Barinaga, M., "Knockout Mice Offer First Animal Model for CF," Science, 257:1046-1047 (1992).
Baudin, A. et al., "A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae," Nucleic Acids Research, 21(14):3329-3330 (1993).
Bollag, R.J. et al., "Homologous Recombination in Mammalian Cells," Annu. Rev. Genet., 23:199-225 (1989).
Bradley, A. et al., "Embryo-Derived Stem Cells: A Tool for Elucidating the Developmental Genetics of the Mouse," Current Topics in Developmental Biology, 20:357-371 (1986).
Chalfie, M. et al., "Green Fluorescent Protein as a Marker for Gene Expression," Science, 263:802-805 (1994).
Chen, C. et al., "Abnormal Fear Response and Aggressive Behavior in Mutant Mice Deficient for .alpha.-Calcium-Calmodulin Kinase II," Science, 266:291-294 (1994).
Christianson, T.W. et al., "Multifunctional yeast high-copy-number shuttle vectors," Gene, 110:119-122 (1992).
Dopf, J. et al., "Deletion mapping of the Aequorea victoria green fluorescent protein," Gene, 173:39-44 (1996).
Dorin, J.R. et al., "Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells," Transgenic Research, 1:101-105 (1992).
Fung-Leung, W-P et al., "CD8 Is Needed for Development of Cytotoxic T Cells but Not Helper T Cells," Cell, 65:443-449 (1991).
Geitz, R.D. et al., "High Efficiency Transformation with Lithium Acetate," In Molecular Genetics of Yeast, A Practical Approach, J.R. Jonston, Ed., pp. 121-134 (1995).
Gu, H. et al., "Deletion of a DNA Polymerase .beta. Gene Segment in T Cells Using Cell Type-Specific Gene Targeting," Science, 265:103-106(1994).
Guthrie, C. et al., Eds. in Methods in Enzymology: Guide to Yeast Genetics and Molecular Biology, vol. 194, Academic Press, pp. 182-187, 239-251, 319-329, 373-388, and 389-398 (1991).
Hamer, R.E. et al., "Production of transgenic rabbits, sheep and pigs by microinjection," Nature, 315:680-683 (1985).
Hanks, M. et al., "Rescue of the En-1 Mutant Phenotype by Replacement of En-1 with En-2," Science, 269:679-682 (1995).
Hoffman, C.S. et al., "A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli," Gene, 57:267-272 (1987).
Hogan et al. in Manipulating the Mouse Embryo: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor New York, pp. 91-149, 153-197, and 247-267 (1986).
Joyner, A.L. et al., "Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells," Nature, 338:153-156 (1989).
Joyner, A.L., (ed.) in Gene Targeting: A Practical Approach, IRL Press, Oxford University Press, New York, pp. 107-144 and 147-178 (1993).
Knudsen, C.M. et al., "Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death," Science, 270:96-99 (1995).
Koller, B.H. et al., "Toward an animal model of cystic fibrosis: Targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells," Proc. Natl. Acad. Sci., USA, 88:10730-10734 (1991).
Lorenz, M.C. et al., "Gene disruption with PCR products in Saccharomyces cerevisiae," Gene, 158:113-117 (1995).
Luo, Y. et al., "A Novel Method for Monitoring Mycobacterium bovis BCG Trafficking with Recombinant BCG Expressing Green Fluorescent Protein," Clinical Diagnostic Laboratory Immunology, 3(6):761-786 (1996).
Lutz, C.T. et al., "Syrinx 2A: An improved .lambda. phage vector designed for screening DNA libraries by recombination in vivo," Proc. Natl. Acad. Sci., USA, 84:4379-4383 (1987).
Manivasakam, P. et al., "Micro-homology mediated PCR targeting in Saccharomyces cerevisiae," Nucleic Acids Research, 24(14):2799-2800 (1995).
Marx, J., "Knocking Genes In Instead of Out," Science, 269:636 (1995).
Michaud, E.J. et al., "The embryonic lethality of homozygous lethal yellow mice (A.sup.y /A.sup.y) is associated with the disruption of a novel RNA-binding protein," Genes & Development, 7:1203-1213 (1993).
Miki, Y. et al., "A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1," Science, 266:66-71 (1994).
Mansour, S.L. et al., "Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes," Nature, 336:348-352 (1988).
Moyer, J.H. et al., "Candidate Gene Associated with a Mutation Causing Recessive Polycystic Kidney Disease in Mice," Science, 264:1329-1333 (1994).
Oldenbburg, K.R. et al., "Recombination-mediated PCR-directed plasmid construction in vivo in yeast," Nucleic Acids Research, 25(2):451-452 (1997).
Orr-Weaver, T.L. et al., "Fungal Recombination," Microbiological Reviews, 49(1):33-58 (1985).
Robertson, E.J. (ed.) in Teratocarcinomas and embryonic stem cells, a practical approach, IRL Press, Washington D.C., pp. 113-181 (1987).
Sambrook et al., Molecular Cloning: A Laboratory Manual, section p. 1.19, 1.74,-1.75, 2.6, 8.2-8.86, and 9.2-9.58 Cold Spring Harbor Laboratories (1989).
Seed, B., "Purification of genomic sequences from bacteriophage libraries by recombination and selection in vivo," Nucleic Acids Research, 11(8):2427-2445 (1983).
Sikorski, R.S. et al., "A System of Shuttle Vectors and Yeast Host Strains Designed for Efficient Manipulation of DNA in Saccharomyces cerevisiae," Genetics, 122:19-27 (1989).
Silva, A.J. et al., "Deficient Hippocampal Long-Term Potentiation in .alpha.-Calcium-Calmodulin Kinase II Mutant Mice," Science, 257:201-206 (1992).
Snouwaert, J.N. et al., "An Animal Model for Cystic Fibrosis Made by Gene Targeting," Science, 257:1083-1088 (1992).
Soriano et al., "Targeted Disruption of the c-src Proto-Oncogene Leads to Osteopetrosis in Mice," Cell, 64:693-702 (1991).
Storck, T. et al., "Rapid construction in yeast of complex targeting vectors for gene manipulation in the mouse," Nucleic Acids Research, 24(22):4594-4596 (1996).
Tavtigian, S.V. et al., "The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds," Nature Genetics, 12:333-337 (1996).
Thomas, K.R. et al., "Site-Directed Mutagenesis by Gene Targeting in Mouse Embryo-Derived Stem Cells," Cell, 51:503-512 (1987).
Travis, J. "Scoring a Technical Knockout in Mice," Science, 256:1392-1394 (1992).
Veis, D.J. et al., "Bcl-2-Deficient Mice Demonstrate Fulminant Lymphoid Apoptosis, Polycystic Kidneys, and Hypopigmented Hair,"Cell, 75:229-240 (1993).
Wang, N. et al., "Impaired Energy Homeostasis in C/EBP.alpha. Knockout Mice," Science, 269:1108-1112 (1995).
Zhang, Y. et al, "Positional cloning of the mouse obese gene and its human homologue," Nature, 372: 425-432 (1994).
Amgen Inc.
Ketter James
LandOfFree
Efficient construction of gene targeting using phage-plasmid rec does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Efficient construction of gene targeting using phage-plasmid rec, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Efficient construction of gene targeting using phage-plasmid rec will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2035589