Efficient cell fusion process

Details Efficient cell fusion process Efficient cell fusion process

1985-08-13

1989-02-21

Tarcza, John Edward

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4351723, 43524026, 43524027, 435948, 935 99, 935100, 935101, 935109, C12N 1500, C12N 502, C12N 500, C12R 191

Patent

active

048064769

ABSTRACT:
Cell fusion is induced between tumor cells that do not secrete a desired protein and mammalian cells or microcells derived from mammalian cells which secrete the desired protein, by substantially removing at least calcium ions to destabilize the cell membranes, adding a fusogen to the destabilized cells, and then adding back polyvalent cations.

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