Effervescent granules and methods for their preparation

Details Effervescent granules and methods for their preparation Effervescent granules and methods for their preparation

1997-09-19

2000-06-06

Harrison, Robert H.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424464, 424489, 424490, A61K 946, A61K 916, A61K 920

Patent

active

060715391

ABSTRACT:
According to the present invent, effervescent granules having a controllable rate of effervescence are provided. Such granules comprise an acidic agent, an alkaline agent, a hot-melt extrudable binder capable of forming a eutectic mixture with the acidic agent and, optionally, a plasticizer. The effervescent granules are made by a hot-melt extrusion process.

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