Effervescent enteric coated L-dopa formulation and method of usi

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 44, 424177, A61K 922, A61K 946, A61K 930

Patent

active

039610411

ABSTRACT:
Therapeutic levels of L-DOPA are achieved by orally administering a pharmaceutical effervescent-enteric coated tablet comprising:

REFERENCES:
patent: 3131123 (1964-04-01), Masquelier
patent: 3891696 (1975-06-01), Bodor et al.
Sandler, M. et al. Lancet Feb. 16, 1974 pp. 238-240 Variation of Levodopa Metabolism with Gastrointestinal Absorption Site.
Eckstein, B. et al. Lancet Feb. 24, 1973 pp. 431-432 Sustained-Release Levodopa in Parkinsonism.
Curzon, G. et al. Lancet Apr. 7, 1973 p. 781 Sustained-Release Levodopa in Parkinsonism.
Voller, G. W. et al. Acta Neurol Scand 50(3): 391-393 (1974) Efficacy of and Possible Differences in Tolerance to L-DOPA Tablets with Different Rates of Release of the Active Substance.

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