Effervescent composition and method of making same

Details Effervescent composition and method of making same Effervescent composition and method of making same

1986-06-30

1987-07-07

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Gas produced in situ by chemical reaction

424156, 424466, 514819, 514474, A61K 3310

Patent

active

046786619

ABSTRACT:
Effervescent granulates, particularly for the manufacture of effervescent tablets, comprising at least one solid, crystalline edible organic acid and at least one carbonate which releases carbon dioxide upon reaction with the organic acid, the acid crystals comprising a coating which contains calcium carbonate adhering to the surface of the acid crystals by means of a bonding layer formed by a reaction at the interface with the crystal of a calcium carbonate coating material. The coating is built up in multi-layers and includes at least two carbonate layers, the layer which is bonded essentially to the acid crystal being composed of calcium carbonate with the succeeding layers adhering to the carbonate layer by means of a bonding layer formed by reaction of the acid and the carbonate. The invention also deals with methods of manufacture as well as fields of use for the new effervescent granulates.

REFERENCES:
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patent: 3556803 (1971-01-01), Ehrreich et al.
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patent: 4339428 (1982-07-01), Tencza
patent: 4417993 (1983-11-01), Gergely
patent: 4446135 (1984-05-01), Fountaine

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