Effervescent antacid and analgesic compositions

Details Effervescent antacid and analgesic compositions Effervescent antacid and analgesic compositions

1985-06-11

1987-11-03

Brown, J. R.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Gas produced in situ by chemical reaction

514629, 514819, 514957, 514960, 424466, A61L 904, A61K 3116, A61K 300

Patent

active

047042699

ABSTRACT:
Disclosed are water soluble effervescent antacid, analgesic powder and tablet formulations which in a preferred embodiment are sodium, sucrose and aspirin free. The formulation is administered through the ingestion of an aqueous solution of the powder or tablet.
The powder and tablet formulations of this invention preferably comprise a therapeutically effective amount of acetaminophen as the analgesic and an effective amount of agglomerated particles of an antacid and a food grade acid which will react in an aqueous solution to produce visible gaseous effervescence.
The formulations of this invention preferably also comprise flavorants, which improve the taste and lubricants and hardening agents which aid in tableting the formulation.

REFERENCES:
patent: 3024165 (1962-03-01), Murphy
patent: 3495001 (1970-02-01), Leonards
patent: 4083951 (1978-04-01), Goudie et al.
patent: 4093710 (1978-06-01), Sass et al.
patent: 4309408 (1982-01-01), Pathak et al.
Chem Abst., 98:1323382, 1983.

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