Effector conjugates, process for their production and their...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S365000, C514S372000, C514S374000, C546S268100, C548S146000, C548S206000, C548S215000, C549S357000

Reexamination Certificate

active

07129254

ABSTRACT:
Conjugates of epothilones and epothilone derivatives (as effectors) with suitable biomolecules (as recognition units) are described. Their production is carried out by the effectors being reacted with suitable linkers, and the compounds that are produced are conjugated to the recognition units. The pharmaceutical use of the conjugates for treating proliferative or angiogenesis-associated processes is described.

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