Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-10-07
1997-07-08
Jacobson, Dian C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
4241851, 4242751, 530300, 530324, 530858, A61K 3564, A61K 3935, C07K 116, C07K 14435
Patent
active
056461151
ABSTRACT:
The present invention is directed to a novel product and method for isolating ectoparasite saliva proteins, and a novel product and method for detecting and/or treating allergic dermatitis in an animal. The present invention includes a saliva protein collection apparatus capable of collecting ectoparasite saliva proteins substantially free of contaminating material. The present invention also relates to ectoparasite saliva proteins, nucleic acid molecules having sequences that encode such proteins, and antibodies raised against such proteins. The present invention also includes methods to obtain such proteins and to use such proteins to identify animals susceptible to or having allergic dermatitis. The present invention also includes therapeutic compositions comprising such proteins and their use to treat animals susceptible to or having allergic dermatitis.
REFERENCES:
patent: 5356622 (1994-10-01), Heath
Benjamini et al., "Allergy to Flea Bites. IV. In Vitro Collection and Antigenic Properties of the Oral Secretion of the Cat Flea, Ctenocephalides felis felis (Bouche)", pp. 143-154, 1963, Exp. Parasitol., vol. 13.
Benjamini et al., "Allergy to Flea Bites. III. The Experimental Induction of Flea Bite Sensitivity in Guinea Pigs by Exposure to Flea Bites and by Antigen Prepared from Whole Flea Extracts of Ctenocephalides felis felis", pp. 214-222, 1960, Exp. Parasitol., vol. 10.
Greene et al., "Characterization of Allergens of the Cat Flea, Ctenocephalides felis: Detection and Frequency of IgE Antibodies in Canine Sera", pp. 69-74, 1993, Parasite Immunol., vol. 15.
Halliwell et al., "The Role of Basophils in the Immunopathogenesis of Hypersensitivity to Fleas (Ctenocephalides felis) in Dogs", pp. 203-213, 1987, Vet. Immunol. Immunopathol., vol. 15.
Keep et al., "Whole Flea Extract as a Desensitising Agent in Canine Summer Dermatitis", pp. 425-426, 1967, Austral. Vet. J., vol. 43.
Kristensen et al., "A Study of Skin Diseases in Dogs and Cats. V. The Intradermal Test in the Diagnosis of Flea Allergy in Dogs and Cats", pp. 414-423, 1978, Nord. Vet.-Med., vol. 30.
Michaeli et al., "In Vitro Studies on the Role of Collagen in the Induction of Hypersensitivity to Flea Bites", pp. 402-406, 1966, J. Immunol., vol. 97, No. 3.
Michaeli et al., "The Role of Collagen in the Induction of Flea Bite Hypersensitivity", pp. 162-170, 1965, J. Immunol., vol. 95, No. 1.
Van Winkle, "An Evaluation of Flea Antigens Used in Intradermal Skin Testing for Flea Allergy in the Canine", pp. 343-354, 1981, J. Amer. Anim. Hosp. Assoc., vol. 17.
Wade et al., "Survival and Reproduction of Artificially Fed Cat Fleas, Ctenocephalides felis Bouche (Siphonaptera: Pulicidae)", pp. 186-189, 1988, J. Med. Entomol., vol. 25, No. 3.
Young et al., "Allergy to Flea Bites. V. Preliminary Results of Fractionation, Characterization, and Assay for Allergenic Activity of Material Derived from the Oral Secretion of the Cat Flea, Ctenocephalides felis felis", pp. 155-166, 1963, Exp. Parasitol., vol. 13.
Frank Glenn R.
Hunter Shirley Wu
Wallenfels Lynda
Heska Corporation
Jacobson Dian C.
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