Ectoparasite saliva proteins and apparatus to collect such prote

Details Ectoparasite saliva proteins and apparatus to collect such prote Ectoparasite saliva proteins and apparatus to collect such prote

1996-04-10

1998-11-24

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 536 231, A61K 3800, A01N 3718, C07H 2102

Patent

active

058406956

ABSTRACT:
The present invention is directed to a novel product and method for isolating ectoparasite saliva proteins, and a novel product and method for detecting and/or treating allergic dermatitis in an animal. The present invention includes a saliva protein collection apparatus capable of collecting ectoparasite saliva proteins substantially free of contaminating material. The present invention also relates to ectoparasite saliva proteins, nucleic acid molecules having sequences that encode such proteins, and antibodies raised against such proteins. The present invention also includes methods to obtain such proteins and to use such proteins to identify animals susceptible to or having allergic dermatitis. The present invention also includes therapeutic compositions comprising such proteins and their use to treat animals susceptible to or having allergic dermatitis.

REFERENCES:
patent: 5356622 (1994-10-01), Heath et al.
Baker et al., 1975, J. Small Anim. Pract., 16 (5):317-327.
Greene et al., 1993, Vet. Immunol. & Immunopathol., 37 (1):15-23.
Halliwell, et al., 1985, Vet. Immunol & Immunopath, 8 (3):215-23.
Kunkle et al., 1985, J. Amer. Vet. Medical Assn., 186 (7):677-80.
McKeon et al., 1994, Int. J. Parasitol., 24(2):259-63.

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