Ectoparasite histamine releasing factor, genes and uses thereof

Details Ectoparasite histamine releasing factor, genes and uses thereof Ectoparasite histamine releasing factor, genes and uses thereof

1998-01-07

2000-05-16

Minnifield, Nita

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

4241841, 4241851, 4241911, 4242651, 4242781, 4242751, 4242761, 530300, 530324, 530325, 530326, 530327, 530328, 530329, 530361, 530858, 435 691, 435 693, C07K 100, C07K 1600, A61K 3900, A61K 1400, A61K 3800

Patent

active

060639024

ABSTRACT:
The present invention relates to ectoparasite histamine releasing factor (HRF) proteins; to ectoparasite HRF nucleic acid molecules, including those that encode such HRF proteins; to antibodies raised against such HRF proteins; and to compounds that inhibit ectoparasite HRF activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to reduce ectoparasite burden of animals.

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