ECR 673: A 7-transmembrane G-protein coupled receptor

Details ECR 673: A 7-transmembrane G-protein coupled receptor ECR 673: A 7-transmembrane G-protein coupled receptor

1999-06-08

2000-08-01

Mertz, Prema

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

435 691, 435 711, 435 712, 435324, 435471, 4352523, 43525411, 4353201, 536 231, 536 235, C07K 14705, C12N 1512, C12N 510, C12N 1563

Patent

active

060968680

ABSTRACT:
ECR673 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ECR673 polypeptides and polynucleotides in therapy, and diagnostic assays for such.

REFERENCES:
Cunningham et al. (1989) Science vol. 244, pp. 1081-1085.
George et al. (1988) Macromolecular Sequencing & Synthesis Ch 12, pp. 127-149, Alan R. Liss, Inc.
B.F. O'Dowd, et al., GenBank Accession No. U66579, Dec. 26, 1996.
Brian F. O'Dowd, et al., "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes", Gene, 187:75-81 (1997).
Jung et al., "Discovery of a Novel Human G Protein-Coupled Receptor Gene (GPR25) Located on Chromosome 1", Biochemical and Biophysical Research Comm., 230, pp. 69-72 (1997).
An et al, "Cloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates Expressed prominently in human lung tissue.", FEBS Letters, 375 pp. 121-124 (1995).
Mahadevan et al, "Isolation of a Novel G Protein-Coupled Receptor (GPR4) Localized to Chromosome 19q13.3", Genomics 30 pp. 84-88 (1995).
Marchese et al., "Cloning and Chromosomal Mapping of three Novel Genes, GPR9, GPR10 and GPR14, Encoding Receptors Related to Interleukin 8, Neuropeptide Y, and Somatostatin Receptors", Genomics 29, pp. 335-344 (1995).

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