Echinocandin pharmaceutical formulations containing...

Details Echinocandin pharmaceutical formulations containing... Echinocandin pharmaceutical formulations containing...

2005-11-01

2005-11-01

Lukton, David (Department: 1653)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S317000, C424S400000, C424S489000

Reexamination Certificate

active

06960564

ABSTRACT:
Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation.

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