Echinatin glycosides

Details Echinatin glycosides Echinatin glycosides

1976-04-01

1978-05-16

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

195 31R, 195 31P, 424180, 424181, 536 5, C07H 1520

Patent

active

040896064

ABSTRACT:
Echinatin glycosides are disclosed having the following formula ##STR1## wherein R.sub.5 and/or R.sub.6 is a glycosyl residue. These substances have pharmacological effects such as the inhibiting action of the echinatin-4'-glucoside on the growth of human lymphoblastoids. These compounds may be chemically synthesized by subjecting a compound of the following formula ##STR2## to reaction with a compound represented by the following formula ##STR3## in which R.sub.1 and/or R.sub.2 is a glycosyl residue or an acyl glycosyl residue, with the optional successive step of subjecting the resultant to reaction with a glycosyl halide or an acyl glycosyl halide.

REFERENCES:
patent: 3876777 (1975-04-01), Horowitz et al.
patent: 3960835 (1976-06-01), Robertson
Noller "Chemistry of Organic Compounds" 3rd Ed., 1965, W. B. Sanders Co., Phila., Pa. pp. 583 and 872.

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