EBV-infected stomach cancer cell line

Details EBV-infected stomach cancer cell line EBV-infected stomach cancer cell line

2007-02-13

2007-02-13

Harris, Alana M. (Department: 1643)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S235100, C435S366000

Reexamination Certificate

active

10320608

ABSTRACT:
An EBV strain infecting epithelial cells and a stomach cancer cell line cancerated by EBV are established to clarify the mechanism of canceration of epithelial cells into stomach cancer by EBV and to develop a chemotherapeutic agent for stomach cancer cancerated by EBV. Further, a stomach cancer cell line stably producing EBV-related antigens is established to develop a diagnostic drug for stomach cancer cancerated by EBV. According to the present invention, GTC-4 cell line was established through culture of stomach cancer tissues. GTC-4 produced the EBV strain infecting epithelial cells and simultaneously produced EBV-related antigens stably in the supernatant.

REFERENCES:
Imai S et al. Journal of Virology 72(5): 4371-4378, 1998.
Shannon-Lowe CD et al. Proc. Natl. Acad. Sci. USA 103(18): 7065-7070, 2006.
Imai et al., J. of Virology, vol. 72, No. 5 (1998) pp. 4371-4378.
Borza et al., J. of Virology, vol. 72, No. 9 (1998) pp. 7577-7582.
Tajima et al., Jpn. J. Cancer Res., vol. 89 (1998) pp. 262-268.
Imai et al., Proc. Natl. Acad. Sci. USA, vol. 91 (1994) pp. 9131-9135.
Shousha et al., J. Clin. Pathol., vol. 47 (1994) pp. 695-698.
Pathmanathan et al., New England J. of Medicine, vol. 333, No. 11 (1995) pp. 693-698.
Epstein et al., Lancet, vol. 1, (1964) pp. 252-253.
Tajima et al., Rinsho to Virus, vol. 25, No. 3 (1997) pp. 169-176. Entire Document in Japanese. Japanese document not considered.

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