Eburnane derivatives, process for their preparation and pharmace

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546 51, A61K 3144, C07D46100

Patent

active

047359463

ABSTRACT:
The invention relates to new eburnane derivatives of the formula (I) ##STR1## wherein R.sup.1 is alkyl having from 1 to 6 carbon atoms, and acid addition salts thereof.
The invention further relates to a process for the preparation of these compounds and pharmaceutical compositions containing them.
Compounds of formula (I) show remarkable CNS-activity and are useful intermediates in the preparation of other, pharmaceutically active compounds.

REFERENCES:
patent: 3753995 (1973-08-01), Martel et al.
patent: 4464535 (1984-08-01), Szantay et al.
patent: 4549020 (1985-10-01), Szantay et al.
patent: 4551462 (1985-11-01), Szantay et al.

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