EBI nucleic acids

Details EBI nucleic acids EBI nucleic acids

1995-05-22

1998-04-07

Feisee, Lila

Chemistry: molecular biology and microbiology

Vector, per se

536 231, 536 235, 536 2431, 536 243, C12N 1511, C12N 1512, C12N 1563

Patent

active

057363897

ABSTRACT:
Inactivation of the APC minor suppressor gene plays an important role in the development of both sporadic and familial forms of colorectal cancers. The majority of these mutations result in the loss of the carboxyl terminus of the APC protein. A cellular protein, EB1, that associates with the carboxyl terminus of APC both in vitro and in vivo has been identified. The EB1 gene is predicted to encode a 268 amino acid protein without significant homology to any protein with known function.

REFERENCES:
Khan et al, Nature Genetics 2:180, 1992.
Berry et al., Nature Genetics 10:415, 1995.
Okubo et al., Nature Genetics 2:173, 1992.
Fukushima et al, Genomics 122:127 1994.
Database Search Results Accession Nos. R13836 Apr. 12, 1995, Q59948 Mar. 16, 1994, X53520 Jun. 27, 1990, S50474 Dec. 1994.
"Screening Recombinant Libraries" Ch. 6, pp. 6.0.3-6.3.5 in Current Protocols in Mol. Biol, 1990.
EMBL Database, Accession No. T03463 Sequence reference HST03463 from human cDNA clone IB327; 24 Aug. 1993 (created).
EMBL Database, Accession No. D12076 Sequence reference HS000S163 from human HepG2 clone S163; 18 Nov. 1992 (created).
Su et al., "APC Binds to the Novel Protein EB1", Cancer Research 55:2972-2977 (1995).
Database Swissport, Accession No. S50474 Sequence reference S50428 of S. cerevisiae cosmid 9537 Dec. 1994.
Sequence djb/D12076, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/T03463, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence dbj/D12080, National Center for Biotechnology (NCBI), Blast Network Jan. 1995.
Sequence emb/Z13306, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/T23427, National Center for Biotechnology Information (MCBI), Blast Network Jan. 1995.
Sequence gb/T31547, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/T30188, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence emb/Z21248, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence emb/Z38235, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/T10870, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence emb/Z21247, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/L36092, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence emb/Z46175, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence emb/Z19434, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/M85402, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence emb/Z15792, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/T11200, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/I03335, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence gb/M74555, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence dbj/D34782, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence dbj/D37609, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.
Sequence fb/U12386, National Center for Biotechnology Information (NCBI), Blast Network Jan. 1995.

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