Early diagnosis of conformational diseases

Details Early diagnosis of conformational diseases Early diagnosis of conformational diseases

2008-04-01

2008-04-01

Campell, Bruce R. (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

C530S350000, C530S402000, C436S536000

Reexamination Certificate

active

10332370

ABSTRACT:
A method for the diagnosis or detection of conformational diseases by assaying for a marker (the pathogenic conformer) of such diseases in a sample is described, which method comprises a cyclic amplification system to increase the levels of the pathogenic conformer which causes such diseases. In particular, such transmissible conformational diseases may be prion encephalopathies. Assays, diagnostic kits and apparatus based on such methods are also disclosed.

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