Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2003-03-26
2008-12-16
Jung, Unsu (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007200, C435S007210, C435S007920
Reexamination Certificate
active
07465555
ABSTRACT:
Diagnostic methods, systems, and kits for identifying patients with systemic inflammatory response syndrome who are likely to progress to sepsis.
REFERENCES:
patent: 5426181 (1995-06-01), Lee et al.
patent: 5484705 (1996-01-01), White et al.
patent: 5566249 (1996-10-01), Rosenlof et al.
patent: 5639617 (1997-06-01), Bohuon
patent: 5780237 (1998-07-01), Bursten et al.
patent: 5804370 (1998-09-01), Romaschin et al.
patent: 5830679 (1998-11-01), Bianchi et al.
patent: 6077665 (2000-06-01), Weirich et al.
patent: 6190872 (2001-02-01), Slotman
patent: 6303321 (2001-10-01), Tracey et al.
patent: 2001/0041177 (2001-11-01), Guyre et al.
patent: 2072103 (1997-01-01), None
patent: 1504597 (1989-08-01), None
patent: WO 03084388 (2003-10-01), None
Baker et al., “In biomarkers we trust?”, Nature Biotechnology, 2005, vol. 23, pp. 297-304.
Bast, Jr, et al., “Translational crossroads for biomarkers”, Clin. Cancer Res., 2005, vol. 11, pp. 6103-6108.
Labaer, “So, you want to look for biomarkers (Introduction to the special biomarkers issue)”, J. Proteome Res., 2005, vol. 4, pp. 1053-1059.
Statsoft, Inc., 1999, Electronic Statistics Textbook, Tulsa, OK, http://www.statsoft.com/textbook/stathome.html.
Davis, “Quantitative neutrophil CD64 expression: Promising diagnostic indicator of infection or systemic acute inflammatory response,” 1996, vol. 16, pp. 121, 124-130.
Knaus, W.A. et al, “The APACHE III Prognostic System*—Risk Prediction of Hospital Mortality for Critically III Hospitalized Adults”,Chest, 100(6):1619-1636 (1991).
Bone, R.C. et al, “Definitions for Sepsis and Organ Failure”,Critical Care Medicine, 20(6):724-726 (1992).
Cheadle, W.G., “The Human Leukocyte Antigens and Their Relationship to Infection”, TheAmerican Journal of Surgery, 165(2A Suppl): 75S-81S (1993).
Roumen, Rudi M.H. et al, “Scoring Systems and Blood Lactate Concentrations in Relation to the Development of Adult Respiratory Distress Syndrome and Multiple Organ Failure in Severely Traumatized Patients”,The Journal of Trauma, 35(5):349-355 (1993).
Wakefield, C.H., et al, “Changes in Major Histocompatibility Complex Class II Expression in Monocytes and T cells of Patients Developing Infection after Surgery”,British Journal of Surgery, 80(2); 205-209 (1993).
Wakefield, C.H., et al, “Polymorphonuclear Leukocyte Activation-An Early Marker of the Postsurgical Sepsis Response”,Arch Surgery, 128:390-395 (1993).
Sauaia, et al, “Early Predictors of Postinjury Multiple Organ Failure”,Arch Surgery, 129:39-45 (1994).
Wagner, D.P., et al, “Daily Prognostic Estimates for Critically Ill Adults in Intensive Care Units: Results from a Prospective, Multicenter, Inception Cohort Analysis”,Critical Care Medicine, 22(9):1359-1372 (1994).
Rangel-Frausto, M.S., et al, “The Natural History of the Systemic Inflammatory Response Syndrome (SIRS)”,Journal of the American Medical Association, 273(2):117-123 (1995).
Asadullah, K., et al, “Immunodepression following Neurosurgical Procedures”,Critical Care Medicine, 23(12):1976-1983 (1995).
Wakefield, C.H., et al, “Surgery and the Release of a Neutrophil Fcγ Receptor”,The American Journal of Surgery, 170:277-284 (1995).
Rixen, D., et al, “Sepsis/SIRS, Physiologic Classification, Severity Stratification, Relation to Cytokine Elaboration and Outcome Prediction in Posttrauma Critical Illness”,The Journal of Trauma: Injury, Infection, and Critical Care, 41(4):581-598 (1996).
Slotman, G.J., et al, “Multivariate Regression Modeling for the Prediction of Inflammation, Systemic Pressure, and End-organ Function in Severe Sepsis”,Shock, 8(3):225-231 (1997).
Van Den Berk, J.M.M., et al, “Low HLA-DR Expression on Monocytes as a Prognostic Marker for Bacterial Sepsis After Liver Transplantation”,Transplantation, 63(12):1846-1848 (1997).
Giannoudis, P.V., et al, “Stimulation of inflammatory markers after blunt trauma”,British Journal of Surgery, 85:986-990 (1998).
Millili, J.J., et al, “Predicting Surgical Outcome Using Bayesian Analysis”,Journal of Surgical Research, 77:45-49 (1998).
Rangel-Frausto, M.S., et al, “The Dynamics of Disease Progression in Sepsis: Markov Modeling Describing the Natural History and the Likely Impast of Effective Antisepsis Agents”,Clinical Infectious Diseases, 27:185-190 (1998).
Weirich, E., et al, “Neutrophil CD11b Expression as a Diagnostic Marker for Early-onset Neonatal Infection”,The Journal of Pediatrics, 132(ss.3,1):445-451 (1998).
De Bont, E.S.J.M., et al, “Plasma IL-8 and IL-6 Levels can be used to Define a Group with Low Risk of Septicaemia Among Cancer Patients with Fever and Neutropenia”,British Journal of Haematology, 107:375-380 (1999).
Ditschkowski, M., et al, “HLA-DR Expression and Soluble HLA-DR Levels in Septic Patients After Trauma”,Annals of Surgery, 229(2):246-254 (1999).
Taniguichi., et al, “Change in the Ratio of Interleukin-6 to Interleukin-10 Predicts a Poor Outcome in Patients with Systemic Inflammatory Response Syndrome”,Critical Care Medicine, 27(7):1262-1264 (1999).
Takala, A., et al, “Systemic inflammatory response syndrome without systemic inflammation to acutely ill patients admitted to hospital in a medical emergency”,Clinical Science, 96:287-295 (1999).
Manjuck, J., et al, “Decreased response to recall antigens is associated with depressed costimulatory receptor expression in septic critically ill patients”,Journal Laboratory Clinical Medicine, 135(2):153-160 (2000).
Müller, B., et al, “Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit”,Critical Care Medicine, 4:977-983(2000).
Selberg, O, et al, “Discrimination of sepsis and systemic inflammatory response syndrome by determination of circulating plasma concentrations of procalcitonin, protein complement 3a, and interleukin-6”,Critical Care Medicine, 28(8):2793-2798 (2000).
Slotman, G.J., “Prospectively validated predictions of shcok and organ failure in individual septic surgical patients: the Systemic Mediator Associated Response Test”Critical Care, 4(5) (2000) 319-326.
Nupponen, I, et al, “Neutrophil CD11b Expression and Circulating Interleukin-8 as Diagnostic Markers for Early-Onset Neonatal Sepsis”,Pediatrics, 108(1):1-6 (2001).
Slotman, G.J., “Prospectively validated prediction of physiologic variables and organ failure in septic patients: The Systemic Mediator Associated Response Test (SMART)”, Critical Care Medicine, 30(5):1035-1045 (2002).
Oczenski, W., et al. “HLA-DR as a Marker for Increased Risk for Systemic Inflammation and Septic Complications after Cardiac Surgery”, Intensive Care Medicine, 29:1253-1257 (2003).
Perry, S.E. et al, “Is Low Monocyte HLA-DR Expression Helpful to Predict Outcome in Severe Sepsis?”,Intensive Care Medicine, 29:1245-1252 (2003).
Muller Kobold et al., 2000, “Leukocyte activation in sepsis: Correlations with disease state and mortality,” Intensive Care Medicine, vol. 26: 883-892.
Anderson Stephen J.
Haney Douglas J.
Waters Cory A.
Becton Dickinson and Company
Jung Unsu
Petry Douglas A.
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