E87Ag antigens of Pseudomonas aeruginosa and monoclonal antibodi

Details E87Ag antigens of Pseudomonas aeruginosa and monoclonal antibodi E87Ag antigens of Pseudomonas aeruginosa and monoclonal antibodi

1990-06-13

1992-02-18

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

424 858, 424 88, 424 92, 4351722, 4351723, 43524026, 43524027, 514 54, 530388, 530387, 530808, 536123, A61K 3940, A61K 39104, C08B 3700, C07K 1528

Patent

active

050892622

ABSTRACT:
P. aeruginosa E87Ag antigen comprising polysaccharide fraction with molecular weight of about 27,000 which is contained in lipopolysaccharide of P. aeruginosa; anti-P. aeruginosa human or mouse monoclonal antibody which recognizes said E87Ag antigen; and mouse-human or mouse-mouse hybridoma which produces said monoclonal antibody.
The monoclonal antibody can be used for making diagnosis and therapy of infections with P. aeruginosa.

REFERENCES:
patent: 4285936 (1981-08-01), Pier et al.
Braude et al., Adv. Int. Med., vol. 26, pp. 427-445 (1980).
Teng et al., PNAS (U.S.A.), 82, 1790-94 (Mar. 1985).
Kirkland et al., Journal Immunol., 132(5), 2590-3 (May, 1984).
Sawada et al., J. Inf. Dis., 152(5), 965-70 (Nov. 1985).
MacIntyre et al., Inf. Immun., 52(1), 76-84 (Apr. 1986).
Pier et al., Inf. Immun., 22(3), 908-18, 919-25 (Dec. 1978).
Pollack et al., J. Clin. Invest. 63, 276-86 (Feb. 1979).
Hiernaux et al., Eur. J. Immunol., 12, 797-803 (1982).
Hancock et al., Inf. Imm., 37(1), 166-71 (Jul. 1982).
CA 98-213852q, Rowe et al., "Structure of the core oligosaccharide from the lipopolysaccharide of Pseudomonas aeruginosa PAC1R and its defective mutants", Eur. J. Biochem., 132, pp. 329-37 (1983).
Mutharia et al., "Monoclonal antibodies specific for E. coli J5 lipopolysaccharide: cross-reaction with other gram-negative bacterial species"; Infection and Immunity, 45, pp. 631-36 (1984).
CA 94-63513f, Knirel et al., "Bacterial antigenic polysaccharides, 11, Structure and carbon-13 NMR spectrum of O-specific polysaccharide from Pseudomonas cepacia", Bioorg. Khim., 6, pp. 1851-9 (1980).
CA 87-100398a, Horton et al., "Analytical characterization of lipopolysaccharide antigens form seven strains of Pseudomonas aeruginosa", Carbohydr. Res., 55, pp. 35-47 (1977).

Affiliated with

Also associated with

Rating

E87Ag antigens of Pseudomonas aeruginosa and monoclonal antibodi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with E87Ag antigens of Pseudomonas aeruginosa and monoclonal antibodi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and E87Ag antigens of Pseudomonas aeruginosa and monoclonal antibodi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1821762