Textiles: spinning – twisting – and twining
Patent
1995-05-05
1999-01-12
Zitomer, Stephanie W.
Textiles: spinning, twisting, and twining
536 245, 536 243, 536 2433, 536 231, 435 6, 435 5, 435 912, A61K 4800, C07H 2104, C07H 2102, C12Q 168
Patent
active
058589872
ABSTRACT:
The present invention relates to the discovery that antisense nucleic acids complimentary to an E6AP gene can be used to regulate cellular p53 levels. In general the invention features E6AP antisense constructs which, by inhibiting E6AP activity, can modulate cellular p53 levels in both p53+ transformed cells and in normal cells. The invention also provides methods for treating papillomavirus (PV) induced condition, methods for regulating cellular p53 levels and methods for regulating cellular proliferation.
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Beer-Romero Peggy L.
Draetta Giulio
Rolfe Mark
Arnold Beth E.
Mitotix, Inc.
Rees Dianne
Vincent Matthew P.
Zitomer Stephanie W.
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